Professor Terrance J. Quinn II, Principal Investigator SFOS, University of Alaska Fairbanks, Juneau AK (Phone: 907-796-5457, Email: [email protected]) Ms. Haixue Shen, PhD Graduate Student SFOS, University of Alaska Fairbanks, Juneau AK Dr. Martin Dorn, Co-Investigator Alaska Fisheries Science Center, Seattle WA Dr. James Ianelli, cooperator Alaska Fisheries Science Center, Seattle WA Mr. Ste...

Sean D. Taylor, Jesse J. Salk and Jason H. Bielas Translational Research Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave, Seattle, WA 98109, USA Department of Medicine, University of Washington Medical Center, 1959 NE Pacific St, Seattle, WA 98195, USA Department of Pathology, University of Washington Medical Center, 1959 NE Pacific St, Seattl...

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Withaferin A (WA), a promising anticancer constituent of Ayurvedic medicinal plant Withania somnifera, inhibits growth of MDA-MB-231 and MCF-7 human breast cancer cells in culture and MDA-MB-231 xenografts in vivo in association with apoptosis induction, but the mechanism of cell death is not fully understood. We now demonstrate, for the first time, that WA-induced apoptosis is mediated by reac...

Let Γ be any canonical left cell of the affine Weyl group Wa of type e An−1, n > 1. We describe the lower boundary hyperplanes for Γ, which answer two questions of Humphreys. Let Wa be an affine Weyl group with Φ the root system of the corresponding Weyl group. Fix a positive root system Φ of Φ, there is a bijection from Wa to the set of alcoves in the euclidean space E spanned by Φ. We identif...