The Vertex Separator Problem (VSP) for a graph is to find the smallest collection of vertices whose removal breaks the graph into two disconnected subsets of roughly equal size. In a recent paper (Optimality Conditions For Maximizing a Function Over a Polyhedron, Mathematical Programming, 2013, doi: 10.1007/s10107-013-0644-1), the authors announced a new continuous bilinear quadratic programmin...

Imaging of downgoing first-order free-surface multiples (ghosts) with VSP data can provide a subsurface image with wider coverage, better vertical resolution, and higher-fold than conventional imaging of VSP primary reflections. A problem with VSP downgoing first-order multiple (ghost) imaging is the interference from downgoing high-order multiples, similar to the interference from multiples wh...

The materialization of views promotes the reduction of multidimensional queries’s execution time. However, this materialization has an associated cost that may exceed the cost constraints of a given environment, characterizing the view selection problem (VSP). VSP consists in selecting the best views given a certain cost threshold. Several solutions have been proposed in the literature to try a...

This paper represents a design study of the datapath for a very long instruction word (VLIW) video signal processor (VSP). VLIW architectures provide high parallelism and excellent high-level language programmability, but require careful attention to VLSI and compiler design. Flexible, highbandwidth interconnect, high-connectivity register files, and fast cycle times are required to achieve rea...

We describe the Virtual Standardized Patient (VSP) application, having a computerized virtual person who interacts with medical practitioners in much the same way as actors hired to teach and evaluate patient assessment and interviewing skills. The VSP integrates technologies from two successful research projects conducted at Research Triangle Institute (RTI). AVA TALKTM provides natural langua...

The recognition that angiogenesis is critical for tumor growth has stimulated the development of several agents that interfere with the process of angiogenesis. Of these agents, vascular endothelial growth factor (VEGF) signaling pathway (VSP) inhibitors have gained a prominent role in the treatment of a large variety of cancers. Along with their clinical introduction, treatment with VSP inhibi...

In the present study, neonatal ZU.ICR mice and their mothers were infected with trophozoites of Giardia lamblia clone GS/M-83-H7 expressing the variant surface protein (VSP) H7. The infection experiments included a detailed analysis of the specificities of anti-Giardia immunoglobulin A (IgA) antibodies in mother's milk and a determination of the effects of the milk antibodies on both the growth...

The use of transgenic plants to express orally immunogenic protein antigens is an emerging strategy for vaccine biomanufacturing and delivery. This concept has particular suitability for developing countries. One factor that has limited the development of this technology is the relatively modest levels of accumulation of some antigenic proteins in plant tissues. We used fusion protein design to...

A vegetative storage protein (VSP) with trypsin inhibitor activity in a deciduous tree, Sapindus mukorassi, was characterized by means of sodium dodecyl sulfate-polyacrylamide gel electrophoresis, Western-blot, immuno-histochemical localization, light- and electro-microscopy, together with analysis of proteinase inhibitor activity of the purified VSP in vitro. There were two proteins with molec...

Transgenic engineering of plants is important in both basic and applied research. However, the expression of a transgene can dwindle over time as the plant's small (s)RNA-guided silencing pathways shut it down. The silencing pathways have evolved as antiviral defence mechanisms, and viruses have co-evolved viral silencing-suppressor proteins (VSPs) to block them. Therefore, VSPs have been routi...