نتایج جستجو برای: volume controlled mechanical ventilation
تعداد نتایج: 926537 فیلتر نتایج به سال:
Mechanical ventilation is frequently delivered to patients admitted to intensive care units to reduce the work of breathing (WOB), to improve oxygenation, or to assist ventilation. The interaction between patient and ventilator is complex with respect to a variety of variables including pressure, volume, flow, and time. Yet these variables can be adequately represented by a mathematical model, ...
BACKGROUND High-tidal-volume mechanical ventilation used in patients with acute lung injury (ALI) can induce the release of inflammatory cytokines, as macrophage inflammatory protein-2 (MIP-2), recruitment of neutrophils, and disruption of alveolar epithelial and endothelial barriers. Induced pluripotent stem cells (iPSCs) have been shown to improve ALI in mice, but the mechanisms regulating th...
BACKGROUND Diaphragm electrical activation (EAdi) and the ratio of tidal volume to EAdi (VT/EAdi) may provide clinical information on neuroventilatory efficiency (NVE) in patients being weaned from mechanical ventilation. We tested the hypothesis that residual sedation could interfere with respiratory recovery, by assessing the effects of flumazenil on EAdi and VT/EAdi ratio. METHODS This obs...
Background & Aims: Elimination of carbon dioxide is related to the alveolar ventilation, respiratory rate and tidal volume. The aim of this study to determine the effect of mechanical ventilation with different tidal volumes and constant minute ventilation on the end tidal Co2 and oxygen saturation during general anesthesia and to seek optimum parameters of mechanical ventilation during gener...
BACKGROUND In critically ill patients at risk for organ failure, the administration of intravenous fluids has equal chances of resulting in benefit or harm. While the intent of intravenous fluid is to increase cardiac output and oxygen delivery, unwelcome results in those patients who do not increase their cardiac output are tissue edema, hypoxemia, and excess mortality. Here we briefly review ...
The approach to mechanical ventilation has been revolutionized by new insights into the pathogenesis of respiratory failure in acute respiratory distress syndrome (ARDS). Concepts such as low-volume ventilation, permissive hypercapnia, inverse ratio ventilation, best and intrinsic positive end-expiratory pressure, airway shear, pressure volume curves, inflection points, and prone positioning ha...
Methods.We studied 24 stable patients after coronary artery surgery and=or valve surgery with cardiopulmonary bypass. Patients were randomly assigned to OLC or conventional mechanical ventilation (CMV). In the OLC group, recruitment manoeuvres were applied until PaO2=FIO2 was greater than 50 kPa (reflecting anopen lung). This valuewasmaintained by sufficient positive airway pressure. In the CMV...
BACKGROUND In pressure support ventilation (PSV), a non-variable level of pressure support is delivered by the ventilator when triggered by the patient. In contrast, variable PSV delivers a level of pressure support that varies in a random fashion, introducing more physiological variability to the respiratory pattern. Experimental studies show that variable PSV improves gas exchange, reduces lu...
OBJECTIVES Biologically variable ventilation improves lung function in acute respiratory distress models. If enhanced recruitment is responsible for these results, then biologically variable ventilation might promote distribution of exogenous surfactant to nonaerated areas. Our objectives were to confirm model predictions of enhanced recruitment with biologically variable ventilation using comp...
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