نتایج جستجو برای: vntr تایپینگ

تعداد نتایج: 1809  

Aditya Nath Jha Henu Kumar Verma Lakkakula Venkata Kameswara Subrahmanya Bhaskar, Pradeep Kumar Patra Prafulla Kumar khodiar

Background: Cytokines are cell signaling molecules which upon release by cells facilitate the recruitment of immune-modulatory cells towards the sites of inflammation. Genetic variations in cytokine genes are shown to regulate their production and affect the risk of infectious as well as autoimmune diseases. Intron-3 of interleukin-4 gene (IL-4) harbors 70-bp variable number of tandem repeats (...

Journal: :Journal of clinical microbiology 2010
Nicolas Radomski Virginie C Thibault Claudine Karoui Krystel de Cruz Thierry Cochard Cristina Gutiérrez Philip Supply Frank Biet María Laura Boschiroli

Members of the Mycobacterium avium complex (MAC) are ubiquitous bacteria that can be found in water, food, and other environmental samples and are considered opportunistic pathogens for numerous animal species, mainly birds and pigs, as well as for humans. We have recently demonstrated the usefulness of a PCR-based mycobacterial interspersed repetitive-unit-variable-number tandem-repeat (MIRU-V...

2013
Hamid Reza Razzaghian Lars A. Forsberg Kancherla Reddy Prakash Szymon Przerada Hanna Paprocka Anna Zywicka Maxwell P. Westerman Nancy L. Pedersen Terrance P. O'Hanlon Lisa G. Rider Frederick W. Miller Ewa Srutek Michal Jankowski Wojciech Zegarski Arkadiusz Piotrowski Devin Absher Jan P. Dumanski

Although historically considered as junk-DNA, tandemly repeated sequence motifs can affect human phenotype. For example, variable number tandem repeats (VNTR) with embedded enhancers have been shown to regulate gene transcription. The post-zygotic variation is the presence of genetically distinct populations of cells in an individual derived from a single zygote, and this is an understudied asp...

2013
Subok Lee Kyu-Jam Hwang Mi-Yeoun Park Seon-Do Hwang Hee-Youl Chai Hyuk Chu Sang-Hee Park

OBJECTIVES Brucellosis is the most common bacterial zoonosis in the world. Multilocus variable-number tandem-repeat (VNTR) analysis (MLVA) is a molecular method for genotyping bacterial species. Brucella abortus biovar I was isolated from most of the brucellosis-suspected patients in Korea. This study was conducted to investigate the ability of various MLVA primers that are used for molecular t...

Journal: :Physiological genomics 2004
Christine Dos Santos Daniele Fallin Catherine Le Stunff Sophie LeFur Pierre Bougnères

We performed a genotype-phenotype association study to examine whether the insulin VNTR (INS VNTR) polymorphism located in the insulin gene promoter was associated with changes in insulin response to oral glucose. Two classes of INS VNTR alleles are observed in Caucasians, the "short" class I and the "long" class III. Plasma insulin and glucose concentrations and indices of insulin secretion (I...

Journal: :Genetics and molecular research : GMR 2013
Y-Q Tong J-J Ye Z-H Wang Y-W Zhang F-X Zhan X-H Guan Y-J Geng S-Y Hou Y Li J-Q Cheng Z-X Lu J-F Liu

Ischemic stroke (IS) is a multifactorial disorder, and genetic factors act as important contributors to its onset and progression. Inflammation is a key event that is closely associated with the pathophysiology of IS. The association of genetic polymorphisms of inflammatory cytokines with IS remains poorly understood. We investigated the relationship between the variable number of tandem repeat...

Journal: :Genes, brain, and behavior 2006
J R Wendland M Hampe T K Newman Y Syagailo J Meyer W Schempp A Timme S J Suomi K P Lesch

By conferring allele-specific transcriptional activity on the monoamine oxidase A (MAOA) gene in humans, length variation of a repetitive sequence [(variable number of tandem repeat (VNTR)] in the MAOA promoter influences a constellation of personality traits related to aggressive and antisocial behavior and increases the risk of neurodevelopmental and psychiatric disorders. Here, we have analy...

Journal: :Journal of clinical microbiology 2010
F Naze E Jouen R T Randriamahazo C Simac P Laurent A Blériot F Chiroleu L Gagnevin O Pruvost A Michault

Pseudomonas aeruginosa is an opportunistic pathogen that causes nosocomial infections in intensive care units. Determining a system of typing that is discriminatory is essential for epidemiological surveillance of P. aeruginosa. We developed a method for the typing of Pseudomonas aeruginosa, namely, multiple-locus variable-number tandem-repeat (VNTR) typing with high-resolution melting analysis...

2013
Anna Żaczek Anna Brzostek Arkadiusz Wojtasik Jarosław Dziadek Anna Sajduda

In this study, 155 clinical Mycobacterium tuberculosis isolates were subject to genotyping with fast ligation-mediated PCR (FLiP). This typing method is a modified mixed-linker PCR, a rapid approach based on the PCR amplification of HhaI restriction fragments of genomic DNA containing the 3' end of IS6110 and resolving the amplicons by polyacrylamide gel electrophoresis. The results were compar...

2014
T Kikuchi Y Kobashi T Hirano N Tode A Santoso T Tamada S Fujimura Y Mitsuhashi Y Honda T Nukiwa M Kaku A Watanabe M Ichinose M Drancourt

Factors that can interfere with the successful treatment of Mycobacterium avium lung infection have been inadequately studied. To identify a potent predictor of therapeutic responses of M. avium lung infection, we analyzed variable number tandem repeats (VNTR) at 16 minisatellite loci of M. avium clinical isolates. Associations between the VNTR profiling data and a therapeutic response were eva...

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