نتایج جستجو برای: viral proteins

تعداد نتایج: 678789  

2011
Tetsuro Komatsu Hirohito Haruki Kyosuke Nagata

The adenovirus genome forms chromatin-like structure with viral core proteins. This complex supports only a low level of transcription in a cell-free system, and thus core proteins have been thought to be negative factors for transcription. The mechanism how the transcription from the viral DNA complexed with core proteins is activated in infected cells remains unclear. Here, we found that both...

Journal: :Journal of proteome research 2006
Eden P Go William R Wikoff Zhouxin Shen Grace O'Maille Hirotoshi Morita Thomas P Conrads Anders Nordstrom Sunia A Trauger Wilasinee Uritboonthai David A Lucas King C Chan Timothy D Veenstra Hanna Lewicki Michael B Oldstone Anette Schneemann Gary Siuzdak

Mass spectrometry analysis was used to target three different aspects of the viral infection process: the expression kinetics of viral proteins, changes in the expression levels of cellular proteins, and the changes in cellular metabolites in response to viral infection. The combination of these methods represents a new, more comprehensive approach to the study of viral infection revealing the ...

2014
Rico Rana Bonita J. Biegalke

UL34 is one of the ~50 genes of human cytomegalovirus (HCMV) required for replication in cell culture in human fibroblasts. UL34 encodes highly related early (UL34a) and late (UL34b) proteins that are virtually identical, with the early protein containing an additional 21 amino terminal amino acids. The UL34 proteins are sequence-specific DNA‑binding proteins that localize to the nucleus. The H...

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