نتایج جستجو برای: vilsmeier haack reaction

تعداد نتایج: 412538  

2015
Marion Donnier-Maréchal David Goyard Vincent Folliard Tibor Docsa Pal Gergely Jean-Pierre Praly Sébastien Vidal

Glycogen phosporylase (GP) is a promising target for the control of glycaemia. The design of inhibitors binding at the catalytic site has been accomplished through various families of glucose-based derivatives such as oxadiazoles. Further elaboration of the oxadiazole aromatic aglycon moiety is now reported with 3-glucosyl-5-amino-1,2,4-oxadiazoles synthesized by condensation of a C-glucosyl am...

Journal: :Sleep 2016
Janet M Mullington Sabra M Abbott Judith E Carroll Christopher J Davis Derk-Jan Dijk David F Dinges Philip R Gehrman Geoffrey S Ginsburg David Gozal Monika Haack Diane C Lim Madalina Macrea Allan I Pack David T Plante Jennifer A Teske Phyllis C Zee

Janet M. Mullington, PhD1; Sabra M. Abbott, MD, PhD2; Judith E. Carroll, PhD3; Christopher J. Davis, MS, PhD4; Derk-Jan Dijk, PhD5; David F. Dinges, PhD6; Philip R. Gehrman, PhD7; Geoffrey S. Ginsburg, MD, PhD8; David Gozal, MD, MBA9; Monika Haack, PhD1; Diane C. Lim, MD10; Madalina Macrea, MD, MPH, PhD11,12; Allan I. Pack, MBChB, PhD, FRCP13; David T. Plante, MD14; Jennifer A. Teske, PhD15; Ph...

2012
Alessandro Munafò Jeffrey R. Haack Irene M. Gamba Thierry E. Magin

in Shock Waves by means of a Spectral-Lagrangian Boltzmann Solver Alessandro Munafò∗, Jeffrey R. Haack, Irene M. Gamba∗∗ and Thierry E. Magin∗ ∗Aeronautics/Aerospace department, von Karman Institute for Fluid Dynamics, Chaussée de Waterloo 72, 1640 Rhode-Saint-Genèse, Belgium Department of Mathematics, The University of Texas at Austin, 201 E. 24th Street, Austin, TX 78712, USA ∗∗Department of ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه سیستان و بلوچستان - دانشکده مهندسی عمران 1392

abstract in aggregate, active forms of reactive silica with mineral names are sometimes associated with sand and gravel in concrete mixture. alkali hydroxides originated from alkalis in the cement or other resources form an alkaline silica gel with this reactive silica which becomes swallowed and expanded during time causing damage to concrete. there have been growing researches on alkaline r...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه رازی - دانشکده علوم 1390

in this thesis, a better reaction conditions for the synthesis of spirobarbiturates catalyzed by task-specific ionic liquid (2-hydroxy-n-(2-hydroxyethyl)-n,n-dimethylethanaminium formate), calcium hypochlorite ca(ocl)2 or n-bromosuccinimide (nbs) in the presence of water at room temperature by ultrasonic technique is provided. the design and synthesis of spirocycles is a challenging task becaus...

Journal: :Revue de l’Institut français d’histoire en Allemagne 2009

Journal: :Journal of medicinal chemistry 2005
Pier Giovanni Baraldi Mojgan Aghazadeh Tabrizi Delia Preti Andrea Bovero Francesca Fruttarolo Romeo Romagnoli Naser Abdel Zaid Allan R Moorman Katia Varani Pier Andrea Borea

In this paper we report the synthesis and biological evaluation of a new class of 2-phenyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-ones as A(3) adenosine receptor antagonists. We designed a new route based on the Kira-Vilsmeier reaction for the synthesis of this class of compounds. Some of the synthesized compounds showed A(3) adenosine receptor affinity in the nanomolar range and good selectivit...

In this paper, the physical optics method is used to study the problem of electromagnetic scattering from Haack series nose cone. First, a meshing scheme is introduced which approximates the curvature of the surface by piecewise linear functions in both axial and rotational directions. This results in planar quadrilateral patches and enables efficient determination of the illuminated region and...

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