Heart failure is frequently a result of impaired systolic ventricular performance. We describe a patient with heart failure and a systemic arteriovenous fistula who had left ventricular enlargement and a normal left ventricular ejection fraction, demonstrated by gated cardiac blood pool scanning. The heart failure was relieved by surgical repair of the fistula, but the left ventricular ejection...

THE electrocardiographic diagnosis of atrial enlargement is a common problem. The established criteria, based on voltage, configuration, and duration of the P wave, very often fail to confirm the diagnosis even in cases of known atrial enlargement. In 1958, Macruz, Perloff, and Case1 proposed a simple formula for electrocardiographic recognition of right, left, and combined atrial enlargement. ...

OBJECTIVE To examine how fetal and infant growth are related to left ventricular mass in adult life. DESIGN A follow up study of men born during 1920-30 whose birth weights and weights at 1 year were recorded. SETTING Hertfordshire, England. SUBJECTS 290 men born and still living in East Hertfordshire, England. MAIN OUTCOME MEASURE Left ventricular mass calculated from measurements of i...

Ventricular enlargement in pediatric TBI is a common observation in clinical practice, yet volumetric studies of ventricle volume are sparse. In this study, MRIs and neuropsychological testing were performed on children who had sustained a traumatic brain injury (n=38) and control children (n=34) between the ages of six and eighteen years. Children with traumatic brain injury (mean GCS=9.0) wer...

BACKGROUND AND PURPOSE Ventricular enlargement and white matter lesions are frequent findings on cerebral magnetic resonance imaging scans of elderly subjects. In demented subjects they seem related to the severity of the dementia, but in nondemented subjects their clinical significance is less clear. We investigated the relation of size of the lateral ventricles and white matter lesions with c...

From a compilation of 1411 gross dissections of the hearts from patients who had had recent electrocardiograms prior to death, 62 were found to have frontal QRS axes between +90 and +1800. Thirty-eight exhibited an S1Q3R3 pattern-the second screening criterion basic to consideration for the label of left posterior hemiblock (LPH). Twenty-two of these also had right ventricular free wall weights...

BACKGROUND Dicer, an RNAse III endonuclease critical for processing of pre-microRNAs (miRNAs) into mature 22-nucleotide miRNAs, has proven a useful target to dissect the significance of miRNAs biogenesis in mammalian biology. METHODS AND RESULTS To circumvent the embryonic lethality associated with germline null mutations for Dicer, we triggered conditional Dicer loss through the use of a tam...

Cerebrospinal fluid (CSF) pulsations have been proposed as a possible causative mechanism for the ventricular enlargement that characterizes the neurological condition known as hydrocephalus. This paper summarizes recent work by the authors to anaylze the effect of CSF pulsations on brain tissue to determine if they are mechanically capable of enlarging the cerebral ventricles. First a poroelas...

PURPOSE From neuroradiologic experience, it is evident that the adaptation of the ventricular system secondary to pathologic processes or surgery is not uniform. To describe changes entirely, one must consider, in particular, information about volume and shape. In this study, we address specifically the information encoded in the change of shape. To exemplify the technique, we used time-series ...