Deep venous valves are frequent sites of deep venous thrombosis initiation. However, the possible contribution of the valvular sinus endothelium has received little attention in studies of thrombosis risk. We hypothesized that the endothelium of valve sinus differs from that of vein lumen with up-regulation of anticoagulant and down-regulation of procoagulant activities in response to the local...

BACKGROUND Cerebral venous sinus thrombosis is a rare and potentially life-threatening neurologic manifestation of antiphospholipid syndrome. Oral contraceptive pills (OCP) may increase the risk of vascular events, even in people without family history of venous thrombosis. CASE PRESENTATION A 31-year-old woman with four weeks of constant headache and history of taking OCP for one year has be...

Cerebral sinus venous thrombosis is an uncommon cause of stroke. Three factors usually predispose to venous thrombosis: hypercoagulability states, venous stasis, and blood vessel wall changes.1--3 In patients with thyrotoxicosis, the increased activity of factor VIII,4 amongst others, results in a hypercoagulability state and has been reported as being a factor which predisposes to cerebral sin...

Two patients with dural arteriovenous fistulas (DAVFs) and unsuccessful transarterial embolizations were treated with a technique for selective transvenous embolization. A 5F catheter was advanced from a femoral vein access into the internal jugular bulb and a catheter was navigated through the sinus lumen into the involved cortical veins or the parasinusal venous draining channels of the DAVFs...

Demailly D, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2017-220344 Description An 86-year-old woman with acute blunt head trauma (the patient’s head was hit by a car) 10 days ago, associated with a right occipital fracture and an acute subdural haematoma (treated in the department of neurosurgery by oral prednisone 80 mg once a day) (figure 1), presented with focal left arm motor seizures. At th...

There has been substantial emphasis placed on categorizing recanalization and collateral formation in patients with acute arterial occlusion resulting in ischemic stroke. Such methods of semi-quantitatively classifying the severity of arterial occlusion for prognostic purposes and assessing the response to treatment have become an integral part of clinical studies. However, no such method exist...

Cerebral sinus venous thrombosis is an uncommon cause of stroke. Three factors usually predispose to venous thrombosis: hypercoagulability states, venous stasis, and blood vessel wall changes.1--3 In patients with thyrotoxicosis, the increased activity of factor VIII,4 amongst others, results in a hypercoagulability state and has been reported as being a factor which predisposes to cerebral sin...

Hyperhomocysteinemia can cause cerebral venous thrombosis. Recombinant tissue plasminogen activator is one of the treatment options for cerebral venous thrombosis in selected cases. We present here a 7-year-old boy with homocysteinuria with stroke. MRI of brain showed cerebral venous sinus thrombosis. We successfully treated with intravenous recombinant tissue plasminogen activator. He recovere...

BACKGROUND AND PURPOSE The suboccipital cavernous sinus, a vertebral venous plexus surrounding the horizontal portion of the vertebral artery at the skull base, provides an alternative pathway of cranial venous drainage by virtue of its connections to the cranial dural sinuses, the vertebral venous plexus, and the jugular venous system. Knowledge of the anatomy of this system facilitates interp...

UNLABELLED INTRODUCTION Cerebral venous sinus thrombosis is a rare condition. The most frequent symptoms and signs are headache, focal seizures with or without secondary generalization, unilateral or bilateral paresis and papilledema. We report a case of transverse sinus and superior sagittal sinus thrombosis that presented with diplopia in a pregnant woman. CASE PRESENTATION A 34-year-old...