NEOINTIMAL HYPERPLASIA is generally considered as the major cause of vein graft stenosis and is the leading pathological sign of vein graft disease. Most research on this problem has focused on the inhibition of neointimal growth, based on the hypothesis that the inhibition of neointimal hyperplasia would improve long-term patency of the vein graft. However, the inhibition of cell proliferation...

Room and Beyond To the Editor: Zacharias and colleagues1 report improved survival with radial artery conduits versus vein graft in coronary artery bypass graft (CABG) surgery with left internal mammary artery to left anterior descending artery, as well as better radial patency. This study reinforces previous findings demonstrating superior patency of arterial conduits over vein grafts. Nonethel...

Introduction: Percutaneous transluminal angioplasty (PTA) is the gold standard in management of AVF dysfunction. On other hand, stenosis with PTA induces an acceleration neointimal hyperplasia occurrence restenosis. The aim this study was to assess increase quick blood (Qb) hemodialysis (HD) patients after venoplasty dysfunction and its patency within 3 months post procedure, examine factors as...

Over a seven year period from 1982 to 1989,3337 conduits were created in 3137 patients with end stage renal disease (ESRD) as access for chronic dialysis. These included 2690 side-to-side arteriovenous fistulae (A VF), 168 end-to-side A VFs, 10 autogenous vein grafts, 51 homogenous frozen vein grafts, 109 polytetrafluoroethylene (PTFE) grafts, 209 emergency external arteriovenous shunts, t...

BACKGROUND The objective of the present investigation was to compare the effect of neoadjuvant irradiation on the microvascular anastomosis in cervical bundle using an experimental model in rats. METHODS One hundred forty male Sprague-Dawley rats were allocated into 4 groups: group I, control, arterial microanastomosis; group II, control, venous microanastomosis; group III, arterial microanas...

OBJECTIVE To evaluate the outcomes of major vessel reconstruction as part of surgery to remove sarcomas. DESIGN Retrospective review. SETTING Tertiary academic medical center. PATIENTS Fourteen patients (10 female) with retroperitoneal or extremity sarcomas and major blood vessel involvement who underwent surgery to remove the tumor and had blood vessel reconstruction between 2003 and 200...

BACKGROUND Injury to the saphenous vein endothelium during harvest impacts patency after coronary artery bypass graft surgery. Many centers are adopting endoscopic saphenous vein harvest (ESVH) instead of using the traditional open saphenous vein harvest (OSVH) technique. Our objective was to compare the effects of ESVH and OSVH on the structural and functional viability of saphenous vein endot...

BACKGROUND Our aim was to investigate the effects of lipid-lowering treatment (LLT) on graft patency in coronary artery bypass grafting (CABG) patients. METHODS A total of 209 CABG patients (95 men, 45%) with a total cholesterol level above 200 mg/dL and a low-density lipoprotein level above 100 mg/dL were included. Patients were divided into 2 groups on the basis of administration of LLT aft...

BACKGROUND Access-related problems are one of the major causes of morbidity in elderly patients with chronic kidney disease. The aim of this study was to assess potential risks and benefits in elderly patients comparing forearm arteriovenous fistula (AVF) and perforating vein AVF below the elbow for primary vascular access. METHODS A retrospective comparison of elderly patients (65.7 ± 9.3 ye...

BACKGROUND In the past decade, the radial artery has frequently been used for coronary bypass surgery despite concern regarding the possibility of graft spasm. Graft patency is a key predictor of long-term survival. We therefore sought to determine the relative patency rate of radial-artery and saphenous-vein grafts in a randomized trial in which we controlled for bias in the selection of patie...