Vaddadi and co-workers, from the Baker Heart and Diabetes Research Institute of Melbourne, have examined, in a group of patients with a clinical history of recurrent postural vasovagal syncope, the behaviour of efferent postganglionic muscle sympathetic nerve traffic, directly assessed via the microneurographic technique in the peroneal nerve, during a fainting episode triggered by tilting. The...

Syncope is defined as the transient loss of consciousness with spontaneous recovery, as a result of cerebral hypoperfusion. It is a very common clinical entity.1 Although it is difficult to establish the prevalence and incidence of syncopal episodes, recent data indicate that 9-35% of the Spanish population present some syncopal episode in their lifetime.2,3 There are a variety of causes which ...

1. Brignole M, Alboni P, Benditt D, Bergfeldt L, Blanc JJ, Block PE, van Dijk G, Fitzpatrick A, Hohnloser S, Janousek J, Kapoor W, Kenny RA, Kulakowski P, Masotti G, Moya A, Raviele A, Sutton R, Theodarakis G, Ungar A, Wieling W. Guidelines on Management (Diagnosis and Treatment) of Syncope—Update 2004 Executive Summary. Eur Heart J 2004; 25:2054–2072. 2. Del Rosso A, Bartoletti A, Bartoli P, U...

OBJECTIVES This study assessed the efficacy of oral etilefrine (10 mg three times a day) in preventing a positive response to head-up tilt testing. BACKGROUND Previous reports have suggested that oral etilefrine can be effective either in preventing a positive response to head-up tilt testing or in reducing syncopal recurrences in patients with vasovagal syncope. Up to now most studies assess...

Aim: The pathophysiology of vasovagal syncope (VVS) is not completely understood. Some echocardiographic parameters have been defined to contribute its pathophysiology. However. whether right atrial (RA) and ventricular (RV) functions any impact on development VVS well known. In this study we aimed evaluate the baseline in patients with special focus ventricle atrium functions.
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BACKGROUND Previous reports that used head-up tilt testing and adenosine administration have suggested that adenosine may be an important endogenous mediator that may trigger a vasovagal response in susceptible patients. However, little is known regarding endogenous adenosine plasma levels (APLs) during vasovagal syncope provoked by tilt testing. The aim of this study was to determine whether A...

Syncope is defined as the transient loss of consciousness with spontaneous recovery, as a result of cerebral hypoperfusion. It is a very common clinical entity.1 Although it is difficult to establish the prevalence and incidence of syncopal episodes, recent data indicate that 9-35% of the Spanish population present some syncopal episode in their lifetime.2,3 There are a variety of causes which ...

1997; 77: 273–5. [32] Natale A, Beheiry S, Wase A et al. Occurrence of clinical asystole in patients without evidence of structural heart disease: response to tilt test and follow-up. Circulation 1999; 100: I-245. [33] Fitzpatrick A, Sutton R. Tilting towards a diagnosis in recurrent unexplained syncope. Lancet 1989; 1: 658–60. [34] Strasberg B, Rechavia E, Sagie A et al. The head-up tilt table...

OBJECTIVES We set out to determine the effect of sublingual nitroglycerin (NTG), as used during routine tilt testing in patients with unexplained syncope, on hemodynamic characteristics and baroreflex control of heart rate (HR) and systemic vascular resistance (SVR). BACKGROUND Nitroglycerin is used in tilt testing to elicit a vasovagal response. It is known to induce venous dilation and enha...

Postherpetic neuralgia is a well-studied and somewhat common sequala of herpes zoster leading to intense pain episodes. Pain-induced vasovagal episodes can rarely lead asystole, which fatal potential complication. It crucial have high clinical suspicion asystole when patient presents with severe herpetic syncope. This unique cause 67-year-old Caucasian female who presented syncope caused by pos...