نتایج جستجو برای: vasculo
تعداد نتایج: 144 فیلتر نتایج به سال:
Growth of solid tumors depends largely on the development of a functional vasculature, which has been the focus in anti-tumor therapy since Folkman in 1971 proposed that prohibiting the formation of new vessels could inhibit tumor growth. The recognition of the tumor vascular bed as an important target led to the development of 3 vascular-targeted strategies. I) The anti-angiogenesis strategy t...
L'ostéochondrome ou exostose est la tumeur osseuse primaire bénigne la plus fréquente, elle contient à la fois de l'os et du cartilage et siège le plus souvent au niveau des métaphyses des os longs. Ces tumeurs sont le plus souvent asymptomatiques, en fonction de leur taille, leur emplacement et de leur localisation; leur siège au niveau du fémur proximal est rarement rencontré car la plupart s...
Glioblastoma multiforme (GBM) is the most lethal type of brain tumor. The formation of abnormal, dysfunctional tumor vasculature and glioblastoma stem-like cells (GSCs) are believed to be the major components of the inability to treat these tumors effectively. We analyzed 70 glioblastoma samples by immunohistochemistry and double immunofluorescenc...
BACKGROUND/AIMS Dipeptidyl peptidase 4 (DPP4) inhibitors improve glycemic control in type 2 diabetes, however, their influence on the retinal neurovascular unit remains unclear. METHODS Vasculo- and neuroprotective effects were assessed in experimental diabetic retinopathy and high glucose-cultivated C. elegans, respectively. In STZ-diabetic Wistar rats (diabetes duration of 24 weeks), DPP4 a...
Endogenous protective pathways mitigate the overshooting of inflammation after sterile or infectious injury. Here we report that formyl peptide receptor 2 (Fpr2/3) null mice display a major phenotype with exacerbated vascular inflammation observed postischemia reperfusion (IR) injury of the mesenteric artery, characterized by marked neutrophil adhesion and extravasation as visualized by intravi...
Abstract Background Several strategies based on immune checkpoint inhibitors (ICIs) have been developed or are under investigation for cancer therapy, opening to advantages in outcomes. However, several ICIs-induced side effects emerged these patients, especially a rare but clinically significant cardiotoxicity with high rate of mortality. Purpose We analyzed the differential vasculo and Pembro...
Introduction: Deafness is defined as hearing impairments that can occur at any age and be of genetic or idiopathic origin. They both abruptly gradually. The aim this work to underline the diagnostic above all etiological contribution spiral CT MRI during deafness, which makes it possible orient therapeutic conduct. Materials methods: We conducted a prospective on patients explored in radiology ...
Background Enlarged perivascular spaces (EPVS), quantified on brain imaging, can reflect structural changes of blood vessels or the surrounding fluid filled spaces. EPVS measures are emerging as promising biomarkers cerebral small vessel disease, especially in dementia research. Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is a vascular ne...
Knowledge of the pathological diagnosis before deciding the best strategy for treating parasellar lesions is of prime importance, due to the relative high morbidity and side-effects of open direct approaches to this region, known to be rich in important vasculo-nervous structures. When imaging is not evocative enough to ascertain an accurate pathological diagnosis, a percutaneous biopsy through...
Penile erection is the ultimate vasculo-tissular response to an integrated and complex series of physiological processes elicited by psychological, neural, and hemodynamic events (Giuliano and Rampin, 2000; Saenz de Tejada, 2002). Upon sexual stimulation, penile erection, occurring in response to the activation of proerectile autonomic pathways, is greatly dependent on adequate inflow of blood ...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید