نتایج جستجو برای: vascular endothelial
تعداد نتایج: 297294 فیلتر نتایج به سال:
Background: The immune-mediated responses in vascular cells may include the increased expression of endothelial adhesion molecules, leukocyte rolling and infiltration, cellular lipid dysregulation and vascular smooth muscle cells (VSMCs) differentiation. Investigating the cellular and molecular events involved in the rolling process is useful for treatment or prevention of the vessel stenosis es...
OBJECTIVE The mechanism and role of angiotensin II-induced vascular endothelial injury is unclear. We examined the molecular mechanism of angiotensin (AII)-induced vascular endothelial injury and its significance for hypertensive diastolic heart failure. METHODS AND RESULTS We compared the effect of valsartan and amlodipine on Dahl salt-sensitive hypertensive rats (DS rats). Valsartan improve...
Vascular calcification is the abnormal deposition of calcium phosphate complexes in blood vessels, which regarded as pathological basis multiple cardiovascular diseases. The flowing exerts a frictional force called shear stress on vascular wall. Blood vessels have different hydrodynamic properties due to discrepancies geometric and mechanical properties. disturbance flow bending area branch poi...
The side effects of toxic trace elements such as lead in the exposed subjects have been investigated in past years. Lead disturbs microvascular system, and changes the plasma level of lipids and lipoproteins. In this research the role of lead in plasma lipids and endothelial permeability of aorta were studied. Two groups of white male rabbits were under investigation for forty days. Group I ...
new blood forming vessels are produced by differentiation of mesodermal precursor cells to angioblasts that become endothelial cells (ecs) which in turn give rise to primitive capillary network. human cord blood (hcb) contains large subsets of mononuclear cells (mncs) that can be differentiated into endothelial-like cells in vitro. human mononuclear progenitor cells were purified from fresh umb...
Vascular endothelial growth factor receptor-2 (VEGFR-2); a cell surface receptor for vascular endothelial growth factors, is a key pharmacological target involved in the cell proliferation/angiogenesis. It has been revealed that VEGFR-2 induces proliferation through activation of the extracellular signal-regulated kinases pathway. In this regard, targeting the VEGFR-2 has been considered as an ...
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