in order to evaluate the microvascular anatomy and the interconnections, 101 fixed brains from human cadavers with a mean age of 41.3 years were subjected to objective scrutiny. symmetry was visualized with an unaided eye and measurements made under microscopic magnification technique using a micrometer. classic symmetry was observed in only 19 of the specimens, whereas the rest of the 82 speci...

s s u In recent decades, a great deal has been learned about the histopathology, etiology, and treatment of vascular anomalies, which has caused change in the classification and terminology used to describe these lesions. The International Society for the Study of Vascular Anomalies (ISSVA) classification system, which has been widely embraced by various subspecialists who care for patients wit...

Vascular anomalies represent a heterogeneous group of pathologies of the circulatory system that can affect any type of hematic and /or lymphatic vessel of different diameter or anatomic site. The extreme variability of tissue types and districts involved by these lesions determines a wide heterogeneity of clinical manifestations, resulting in involvement of different medical expertise. In this...

OBJECTIVE Matrix metalloproteinases (MMPs) and the angiogenic proteins basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) have been implicated in mechanisms of human cancer and metastasis. Assays were conducted on the urine of patients with vascular anomalies (tumors and malformations), relatively common and occasionally life-threatening disorders for which few ...

Vascular compression of the tracheobronchial tree frequently presents early in infancy with significant airway compromise. For this reason, the pediatric otolaryngologist is often consulted early in the assessment of these patients. Three unusual cases of tracheobronchial vascular compression are presented. The diagnosis and management of children with tracheobronchial vascular compression is d...

Introduction Congenital anomalies of the kidney exhibit great variety. The major anomalies are fused kidney, ectopic kidney, and malrotated kidney [1]. Because many affected patients are asymptomatic, some anomalies are incidentally found by computed tomography and others are found after death. Recent popularization of kidney transplantation requests has led to an increase in research of the va...

Phakomatosis Pigmentovascularis (PPV) is a rare cutaneous congenital malformation syndrome, defined as simultaneous occurrence of congenital cutaneous vascular and pigmentary anomalies. As most of the reported cases are from Far East countries, especially Japan, we reported a case of PPV type IIa in an Iranian patient. This case was unusual because of the coexistence of unilateral extensive por...

The International Society for the Study of Vascular Anomalies (ISSVA) provides a classification vascular anomalies that enables specialists to unambiguously classify diagnoses. This is only available in PDF format and not machine-readable, nor does it provide unique identifiers allow structured registration. In this paper, we describe process transforming ISSVA into an ontology. We also structu...

INTRODUCTION Haemangiomas in children usually involute spontaneously and surgical treatment is exceptional. Vascular malformations do not regress spontaneously and resection may become necessary. We present a series of surgically treated face and neck vascular anomalies during a 9-year period, assessing the epidemiology, presenting signs and symptoms, diagnostic modalities, indications for surg...

Compression of the airway by vascular anomalies is a co-morbidity occurring frequently in children with congenital heart diseases. Here we presented a cohort of 7 patients with respiratory distress who showed airway compression due to vascular anomalies on evaluated with multidetector computed tompgraphy. The anomalies detected were double aortic arch, left sided aortic arch with aberrant right...