Tramadol is an opioid pain medication used to treat moderate moderately severe pain. When taken by mouth in immediate-release formulation, the onset of relief usually begins within hour. It also available injection. combination with paracetamol (acetaminophen). There are many reported analytical methods for estimation Tramadol. The present work list outs various drug.

In this paper, we derive nonasymptotic error bounds for the Lasso estimator when penalty parameter is chosen using K-fold cross-validation. Our imply that cross-validated has nearly optimal rates of convergence in prediction, L2, and L1 norms. For example, show model with Gaussian noise under fairly general assumptions on candidate set values parameter, estimation converges to zero prediction n...

In this paper, we present the development and validation of a Disaster Management Metamodel, a language that we develop specific for describing disaster management domain, as a foundational component to create a decision support system to unify, facilitate and expedite access to disaster management expertise. The metamodel which consists of four views based on disaster management phases includi...

We present an algorithm for computation of cell adjacencies for well-based cylindrical algebraic decomposition. Cell adjacency information can be used to compute topological operations e.g. closure, boundary, connected components, and topological properties e.g. homology groups. Other applications include visualization and path planning. Our algorithm determines cell adjacency information using...

B lymphocytes promote the initial innate interferon response to viral pathogens without the need for antigen receptor activation. B cell dependent IFN production requires the cytokine, lymphotoxin-β. The LTβ pathway is well known to regulate lymphoid organogenesis and homeostasis by differentiating stromal cells and macrophages. However, in response to viral pathogens these same B cell-regulate...

The development of an asymptotic theory relating to the size of a bandwidth of a variable that is entered into a nonparametric regression is becoming well understood. However, the connections between variables that are smoothed away and those that are tested for significance has not been previously studied. This paper proposes a variety of simulation exercises to examine the performance of both...

As the number of transistors on a chip continues increasing the power consumption has become the most important constraint in processors design. Therefore, to increase performance, computer architects have decided to use multiprocessors. Moreover, recent studies have shown that heterogeneous chip multiprocessors have greater potential than homogeneous ones. We have built a modular simulator for...