OBJECTIVE To investigate the functional implications of CD44 splice variant expression in fibroblast-like synoviocytes (FLS) obtained from patients with rheumatoid arthritis (RA). METHODS FLS were isolated from synovial tissue obtained from both diseased and nondiseased joints. The expression of splice variants containing exons v3 and v6 was analyzed using immunocytochemistry with exon-specif...

Precipitation is one of the integral components global hydrological cycle. Accurate estimation precipitation vital for numerous applications ranging from hydrology to climatology. Following launch Global Measurement (GPM) Core Observatory, Integrated Multi-satellite Retrievals GPM (IMERG) product was released. The IMERG provides estimates at finer spatiotemporal resolution (e.g., 0.1°/half-hour...

We investigated how interactions between monocular motion parallax and binocular cues to depth vary in human motion areas for wide-field visual motion stimuli (110 × 100°). We used fMRI with an extensive 2 × 3 × 2 factorial blocked design in which we combined two types of self-motion (translational motion and translational + rotational motion), with three categories of motion inflicted by the d...

OBJECTIVE - To determine if the application of a continuous electrode paste band on precordial leads results in alteration of the electrocardiographic tracing as compared with an adequate amount of electrode paste, and if the former condition does not cause uniform morphologies from V1 to V6. METHODS - The amplitude and morphology of the electrocardiographic waves on the precordial leads in ele...

The top-of-atmosphere spectral reflectance measured by SCIAMACHY has been validated by comparisons between calibrated SCIAMACHY V6 Level 1 data and corresponding reflectances from AATSR and MERIS. The AATSR analysis is currently restricted to part of one specifically processed orbit containing a scene over a hurricane with high and homogeneous clouds for which results for V5 data are already av...

Pathogens that cause chronic infections often employ antigenic variation to evade the immune response and persist in the host. In Treponema pallidum (T. pallidum), the causative agent of syphilis, the TprK Ag undergoes variation of seven V regions (V1-V7) by nonreciprocal recombination of silent donor cassettes with the tprK expression site. These V regions are the targets of the host humoral i...

The quality of the Nimbus 7 Limb Infrared Monitor of the Stratosphere (LIMS) nitric acid (HNO3) and nitrogen dioxide (NO2) profiles and distributions of 1978/1979 are described after their processing with an updated, Version 6 (V6) algorithm and subsequent archival in 2002. Estimates of the precision and accuracy of both of those species are developed and provided herein. The character of the V...