Uterine artery embolization (UAE) closes the blood supply to the uterine arteries, causing death of the tissue and shrinkage of the fibroids. In UAE the patient is sedated and given only local anesthesia. The procedure is performed by an interventional radiologist. A catheter is inserted through a small incision in the groin and threaded through the femoral artery to the uterine arteries (Figur...

BACKGROUND Uterine fibroids or leiomyoma are a common benign smooth muscle tumor. The tumor growth is well known to be estrogen-dependent. However, the molecular mechanisms of its estrogen-dependency is not well understood. METHODS Differentially expressed genes in human uterine fibroids were either retrieved from published papers or from our own statistical analysis of downloaded array data....

Uterine leiomyomas (fibroids) are the most prevalent medical problem of the female reproductive tract, but there are few non-surgical treatment options. Although many advances in the understanding of the molecular components of these tumors have occurred over the past five years, an effective pharmaceutical approach remains elusive. Further, there is currently no clinical method to distinguish ...

Fibroids are the commonest uterine neoplasms, occurring in 20% - 30% of women of reproductive age. In women who have pelvic masses of unknown cause, unusual manifestations of fibroids such as necrosis or degeneration may simulate a carcinoma or hydrometra resulting in problems with image interpretation. We report a case of an unsuspected large degenerated uterine fibroid in a lady mistakenly di...

Uterine artery embolization (UAE) is a well-accepted treatment for symptomatic uterine fibroids, but endpoints of UAE remain controversial. This significant concern as incomplete can lead to failure, necessitating repeat or alternative treatments such hysterectomy. Multiple potential causes failure have been described including catheterize one both the arteries, spasm, clumping embolic material...

Magnetic Resonance-guided focused Ultrasound Surgery (MRgFUS) is gaining popularity as an alternative to medical and surgical interventions in the management of symptomatic uterine fibroids. Studies have shown that it is an effective non-invasive treatment with minimal associated risks as compared to myomectomy and hysterectomy. MRgFUS can be offered to a majority of patients suffering from sym...

Smptomatic uterine fibroids are estimated to occur in 25-50% of women of reproductive age, causing severe menstrual cramps, menorrhagia (which can result in anemia), reduced fertility, and/or symptoms of pressure, such as urinary frequency, a feeling of heaviness or bloating, or pain due to nerve compression. There are several treatment options for symptomatic fibroids, including myomectomy, hy...

OBJECTIVE To provide recommendations regarding the best management of fibroids in couples who present with infertility. Usual and novel treatment options for fibroids will be reviewed with emphasis on their applicability in women who wish to conceive. OPTIONS Management of fibroids in women wishing to conceive first involves documentation of the presence of the fibroid and determination of li...