Cervical intraepithelial neoplasms The cervical intraepithelial neoplasms (CINs) are abnormalities of the squamous ectocervical epithelium. The first group consists of squamous intraepithelial lesions of low histological stage (LSIL) and includes flat condyloma and CIN I, while the second group consists of squamous intraepithelial lesions of high histological stage (HSIL) including CIN II and C...

OBJECTIVES The purpose of this study is to statistically compare the mean ages of the patients with gynecologic cancer in our hospital during the 2000-2009 interval. MATERIAL AND METHODS The data was collected from the Histopathology Exams (HPE) registers. RESULTS Gynecologic cancer was discovered in 1244 cases: 731 cervical cancers, 392 uterine cancers, 82 ovarian cancers, 31 vulvar cancer...

conclusions spontaneous rupture of pyometra duo to cervical cancer in cases of acute abdomen in elderly patients should be considered. introduction pyometra is an accumulation of purulent material or pus in the uterine cavity. spontaneous perforation of uterus by pyometra is rare. this is a clinical presentation and management of a spontaneous perforation of uterine caused by pyometra. case pre...

abstract carcinoma of the cervix is a common neoplasm and accounts for a considerable number of cervical diseases that lead to death in developing countries. in these countries early detection and improved methods of treatment have resulted in comparatively better control of the cancer and long survival however, invasive and metastatic disease still occurs. the authors present the case report o...

The retinoblastoma gene was the first tumour suppressor gene identified that was altered not only in retinoblastomas but has been described in a wide variety of human neoplasms. The retinoblastoma gene encodes a nuclear phosphoprotein that in its hypophosphorylated state plays an important role in regulating the cell cycle, thus preventing from tumour formation. Expression of retinoblastoma gen...

The present study was designed to determine the effect of the spatial gradient from the cervix to the uterine fundus on the control of local prostaglandin H synthase (PGHS) 2 mRNA expression. We performed total cesarean hysterectomies during the last trimester in 12 pregnant baboons, 7 not in labor and 5 in labor, and examined PGHS2 mRNA expression throughout the uterus. PGHS2 mRNA abundance wa...

Introduction. Thrombosis is a formidable complication of the oncological process that still profoundly contributes to overall mortality despite anticoagulant use. According recent data, thrombosis in cancer represents special type prothrombotic state, wherein thromboinflammationis one its constituents. In addition, thromboinflammation both disease progression and intensity metastasis processes....

Conclusion: Inflammatory lesions were the most common cervical lesions followed by malignancies. Among inflammatory lesions, chronic nonspecific cervicitis was commonly found followed by papillary endocervicitis seen in sexually active females with pelvic inflammatory disease, dysfunctional uterine bleeding, uterine prolapsed, and so on. The most common cervical malignancy was squamous-cell car...

The Gynecologic Oncology Group (GOG) is a large organization with collaboration among institutions in the USA. The group has been active in many important trials involving gynecologic cancers. Until March 2011, 477 protocols were completed (82 phase III, 311 phase II, and other phase I, staging or special studies) while 50 are currently active (1). From the first (GOG 1) to the last trial (GOG ...

BACKGROUND Cervical pregnancy is a rare form of ectopic pregnancy, and the most effective method of its treatment is still under investigation. We would like to call attention to selective uterine artery embolization as an effective modern treatment method. CASE A patient with suspected cervical pregnancy and 7-week amenorrhea was admitted to the hospital after unsuccessful use of emergency c...