I n the 1820s Claude Louis Marie Henri Navier1 was a professor at the École des Ponts et Chaussées in Paris, which was the Grande École that trained engineers in nineteenthcentury France. At the same time as publishing his famous fluid equations (now known as the Navier-Stokes equations), he designed the first monumental suspension bridge to be built in Paris over the Seine. His bridge develope...

BACKGROUND Poliomyelitis was before the immunization an important medical problem. Nowadays polio prior patients (PP) suffer from polio sequelae or have developed post-polio-syndrome (PPS) with increasing paresis, pain and fatigue. OBJECTIVES To analyze the medical situation 50 years after acute polio. The degree of paresis was compared between the recovery 1952-1961 and 2012.The prevalence o...

In the present study, the synthesis and biological evaluation of one novel pyridine and one novel pyridone anticancer compound is reported. The compounds 6‑(2,4‑dimethoxyphenyl)‑4‑(3,4‑methylenedioxyphenyl)‑1H‑pyridin‑2‑one (1) and 2‑(2,4‑dimethoxyphenyl)‑4‑(3,4‑methylenedioxyphenyl)pyridine (2) were synthesized from a chalchone precursor. 1 was more active than 2 in inhibiting the proliferatio...

Reusing the data collected during an epidemiological study is a complex task. This is mainly due to the frequent utilization of traditional storage supports, as well as specific formats and/or terminologies which can make it difficult to integrate the gathered data with data from other information resources. Using terms from the UMLS Metathesaurus, we have annotated the data collected during th...