نتایج جستجو برای: undercarboxylated osteocalcin

تعداد نتایج: 4017  

Journal: :Asia Pacific journal of clinical nutrition 2015
Shozo Yano Toru Nabika Atsushi Nagai Tsuyoshi Hamano Masayuki Yamasaki Minoru Isomura Kuninori Shiwaku Shuhei Yamaguchi Toru Yamaguchi Toshitsugu Sugimoto

OBJECTIVE Undercarboxylated osteocalcin (ucOC) produced from the bone was recently found to play a regulatory role in the insulin and adiponectin secretion. We performed a cross-sectional study to investigate the relationship between ucOC and diabetes mellitus (DM). METHODS We included 1,870 subjects aged over 50 from participants of a health examination. According to the current medication a...

Journal: :Kidney & blood pressure research 2010
Takafumi Okura Mie Kurata Daijiro Enomoto Masanori Jotoku Tomoaki Nagao Veena Rasika Desilva Jun Irita Ken-Ichi Miyoshi Jitsuo Higaki

The development of vascular calcification is an active, highly regulated process with similarities to bone formation. Osteocalcin (OC), a vitamin K-dependent protein expressed by osteoblasts, contains 3 gamma-carboxyglutamic acid residues derived from the vitamin K-dependent posttranslational modification of glutamic acid residues. Circulating undercarboxylated OC (ucOC) is increased in vitamin...

Journal: :The American journal of clinical nutrition 2004
Heidi J Kalkwarf Jane C Khoury Judy Bean James G Elliot

BACKGROUND Vitamin K has been suggested to have a role in bone metabolism, and low vitamin K intake has been related to low bone density and increased risk of osteoporotic fracture. OBJECTIVE The objective of this study was to determine whether phylloquinone (vitamin K(1)) intake and biochemical indicators of vitamin K status are related to bone mineral content (BMC) and markers of bone forma...

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