Purpose: To investigate the activity of Feronia elephantum fruit pulp extract (which is used in folk medicine) against indomethacin-induced gastric ulcer in rats. Methods: The fruit pulp was extracted with ethanol and the anti-ulcer activity of the extract in indomethacin-induced gastric ulceration in Swiss albino rats was evaluated. The parameters assessed were pH and acid concentration of gas...

BACKGROUND Diabetic foot ulcer is a worldwide health care concern affecting tens of thousands of patients. If these ulcers left untreated, they can create severe complications. OBJECTIVES This study was designed to examine the effect of infrared radiation on the healing of diabetic foot ulcer. PATIENTS AND METHODS This clinical trial was performed on 50 patients referred to Dr. Ganjavian ho...

Pain is an ever-present problem in patients with pressure ulcers. As an advocate for persons with pressure ulcers, the National Pressure Ulcer Advisory Panel (NPUAP) is concerned about pain. To synthesize available pressure ulcer pain literature, a systematic review was performed of English language literature, specific to human research, 1992 to April 2008, using PubMed and the Cumulative Inde...

Most of the currently available oral antiulcer drugs for the treatment of peptic ulcer provoke detrimental adversative effects. Hence, the exploration for plant-derived products for the treatment of ulcer continues. Syringin, a phenylpropanoid glucoside found in the tepals of Musa Paradisiaca, has many biological properties, including as an antioxidant, immunomodulatory and antidiabetic agent. ...

BACKGROUND Melissa officinalis (MO) has potent antioxidant activity. Recent research has demonstrated the anti-ulcer properties of some medicinal plants through their antioxidant properties. OBJECTIVES The aim of this study was to evaluate the effects of methanolic extracts of MO on experimental gastric ulcers in rats. MATERIALS AND METHODS Male Wistar rats (200 - 250 g) were starved for 24...

Objective: To determine the clinical outcome of laparoscopic versus open repair perforated peptic ulcer. Study Design: Comparative analytical study Place and Duration Study: Department Surgery Ward-2, Jinnah Postgraduate Medical Centre Karachi from 1st March 2021 to 28th February 2022. Methodology: Fifty patients with duodenal ulcer perforation were divided into two equal groups surgery or was ...

IntroductionAmong Diabetes Mellitus (DM) patients, Diabetic Foot Ulcer (DFU) is the most prevalent complication that affects patients' quality of life (QoL). The present study aims to translate, validate, and test reliability Scale-Short Form (DFS-SF) in Malayalam language.MethodologyThe DFS-SF questionnaire was translated language using Mapi Research Trust translation guidelines. content valid...

BACKGROUND Avipattikar churna, a poly-herbal formulation, is one of the popular ayurvedic formulations which is used for peptic ulcer diseases but the scientific documentation with regards to its effect for the indication is lacking. AIMS This study was carried out to evaluate the anti-secretory and the anti-ulcerogenic activities of the churna and to compare its activity with that of ranitid...

BACKGROUND In various studies, Cydonia oblonga Miller (quince) has been reported to have many properties such as antioxidant and anti-ulcerative effects. This study has aimed to investigate the protective effects of quince aqueous extract (QAE) and quince hydroalcoholic extract (QHE) on gastric ulcer caused by indomethacin and the relevant macroscopic, histopathology, and biochemical factors in...