CONTEXT Ulcer is the most common gastrointestinal disturbance resulting from an inadequate gastric mucosal defense. Several drugs are available in the market to address the disease; however, these drugs are associated with unnecessary side effects. OBJECTIVES Previous research have confirmed the efficacy of plant extracts for possible treatment of the disease. This research aims to evaluate t...

Cymbopogon citratus is a medicinal plant popularly used in Brazil for the treatment of various diseases, and the research interest in this plant is justifiable because of its potential medicinal value in stomachache and gastric ulcer. This study was aimed to test the validity of this practice by using experimental models of gastric ulcer and to clarify the mechanisms of gastroprotection by C. c...

A single-blind, randomized controlled trial was conducted to evaluate vacuum-compression therapy (VCT) for the healing of diabetic foot ulcers. Eighteen diabetic patients with foot ulcers were recruited through simple nonprobability sampling. Subjects were randomly assigned to either an experimental or a control group. Before and after intervention, the foot ulcer surface area was estimated ste...

Author E-mail: [email protected] Tel: (+966) 11-4695784; Fax: (+966) 11-4677710 Onion (Allium cepa L.) is one of the most widely consumed culinary vegetables globally. Onions are a rich source of dietary flavonoids and other bioactive compounds. Its consumption offers protection against a wide range of gastrointestinal disorders. We used a rat model with gastric mucosal injury to simulate gast...

Peptic ulcer disease is a widely prevalent upper gastrointestinal disorder worldwide. Gastric hypersecretion is recognized as the prime underlying cause of this disease. Earlier approaches towards alleviation of this disease have primarily focussed on symptomatic treatment of gastric hypersecretion with anti-secretory agents. Histamine H2 receptor antagonists represented the first successful me...

Introduction: Pressure ulcers are a significant cause of morbidity and mortality, source considerable expense in health expenditures. Bacteremia is frequently seen complication pressure ulcers, although its incidence has yet to be well defined, there scarce studies on the subject. The aim present study assess frequency bacteremia ulcer origin as an indicator decisions start systemic antibiotics...

For the last three centuries, Bismuth compounds have been of traditional importance for the treatment of infectious diseases, syphilis, amoebiasis, dyspepsia and diarrhea 1. Despite its old history, intensive research and investigation on the mechanism of action and its clinical efficacy has begun in recent years.Trivalent bismuth preparations such as bismuth subsalicylate (BSS) and colloidal b...

Cardiospermum halicacabum L. var. microcarpum (Kunth) Blume and var. luridum (Blume) Adelb. (Sapindaceae) are used for various ailments in Indian traditional medicines. The present study evaluated the antiulcerogenic property of seed oils (Petroleum ether extracts) in animal model. Ethanol induced gastric ulcers was used for this study and analysed for gastric volume, ulcer score pH, free and t...