BACKGROUND AIMS Mesenchymal stromal cells (MSC) have been observed to participate in tissue repair and to have growth-promoting effects on ex vivo co-culture with other stem cells. METHODS In order to evaluate the mechanism of MSC support on ex vivo cultures, we performed co-culture of MSC with umbilical cord blood (UCB) mononuclear cells (MNC) (UCB-MNC). RESULTS Significant enhancement in ...

Umbilical cord blood (UCB) is increasingly used as a source of hematopoietic progenitor cells to treat a variety of disorders. UCB transplant is associated with comparatively reduced incidence of graft-versus-host disease, robust graft versus leukemia effect, and relatively high incidence of opportunistic infections, three processes in which donor-derived T lymphocytes are known to be predomina...

There exist an elliptical confidence region for the w, as described in the following theorem Theorem 1. ([2], Theorem 2) Assuming ‖w‖ ≤ √ d and ‖xt‖ ≤ √ d, with probably 1− δ, we have w ∈ Ct, where Ct = { z : ‖z − ŵt‖Mt ≤ 2 √ d log Td δ } For any x ∈ A, we define UCBx,t = maxz∈Ct z′x if w ∈ Ct (which holds with high probability). At each time, the UCB algorithm then simply picks the bandit with...

The procedures for collecting voluntarily and freely donated umbilical cord blood (UCB) units and processing them for use in transplants are extremely costly, and the capital flows thus generated form part of an increasingly pervasive global bioeconomy. To place the issue in perspective, this article first examines the different types of UCB biobank, the organization of international registries...

U p b nformation about umbilical cord blood (UCB) banking is surfacing at a very rapid pace. The messages, argely targeted toward women, encourage motherso-be to bank their child’s UCB. Indeed, an everrowing number of Internet sites and magazine adertisements are cautioning women that storing a ewborn’s UCB is a once-in-a-lifetime opportunity nd a worthwhile investment that can save their child...

These results allow us to conclude that [18F]UCB-H is a suitable radiotracer for the imaging of the isoform SV2A in vivo. Forty male Sprague-Dawley were divided in two experiments SV2A is a SV2 isoform protein involved in the synaptic vesicle trafficking and in brain process like the epilepsy (1, 2). [18F]UCB-H was developed like a tool to study the role of this isoform with neuroimaging techni...

Allogeneic stem cell transplantation with umbilical cord blood (UCB) cells is limited by the cell dose a single unit provides recipients. Ex vivo expansion is one strategy to increase the number of cells available for transplantation. Aastrom Biosciences developed an automated continuous perfusion culture device for expansion of hematopoietic stem cells (HSCs). Cells are expanded in media suppl...

Recent functional studies have suggested that, in addition to simple diffusion, carrier-mediated transport may play an important role in foetal unconjugated bilirubin (UCB) uptake by the placenta. We have investigated the role of organic anion-transporting polypeptides (OATPs) in UCB transport by the placenta-maternal liver tandem. RNA was obtained from human liver (hL), human placenta (hPl) at...

1 University of Colorado at Boulder, Department of Computer Science, 430 UCB, Boulder, CO 80309, USA, [email protected] 2 Old Dominion University, Department of Computer Science, 3300 ECS Building, Norfolk, VA 23529, USA, [email protected] 3 University of Colorado at Boulder, Department of Computer Science, 430 UCB, Boulder, CO 80309, USA, [email protected] 4 Columbia Univers...

s for most PATHresearch publications can alsobe obtained via the PATH WorldWide Web internet site at:http://www.path.berkeley.eduAn Updated List of Recent PATH Sponsored Research PublicationsPATH on Paper Smart Call Box Field Operation Test Evaluation:Summary Report, James H. Banks, Patrick A.D. Powell,January 1997, $10.00UCB-ITS-PRR-97-3 Collision Analysis o...