objectives: since problem solving group training is a comprehensive, active program and based-on cognitive behavioral approach, the aim of present study was to determine the effectiveness of problem solving therapy on depression and coping style in patients with type 2 diabetes mellitus. methods: in an experimental design the study was done with pretest-posttest with control group. totally 30 f...

objective: dm is a major medical problem in developing countries such as iran. blood sugar and lipids levels increase in diabetics exacerbates the onset of diabetes mellitus (dm) late complications. researchers have focused on herbal medicines improve sugar and lipid levels against side decreasing effects and possible inefficacy of chemical drugs. this study has assessed the effect of curcumin ...

abstract objective: it has been reported that adenosine deaminase (ada) is a good marker for insulin function but its clinical significance in type 2 diabetes mellitus (t2dm) is not yet characterized. this study aims to assess the association of ada with glycated hemoglobin (hba1c) and uric acid (ua) in t2dm patients. materials and methods: the study population consisted of 120 subjects divided...

objective: due to the increased prevalence of thyroid dysfunction in subjects with type 2 diabetes and also this fact that antibodies could potentially identify subjects at risk of thyroid dysfunction, this study was conducted to investigate thyroid autoimmunity in type 2 diabetic patients. material and methods: among patients referred to yazd diabetes research center, 4000 type 2 diabetic pati...

recent studies suggested the role of white blood cells (wbcs) in the pathogenesis and complications of type 2 diabetes. increased wbc counts predict mortality in patients with chronic kidney disease (ckd). in this study alterations in wbc subpopulations in diabetic patients with non-dialysis dependent ckd are investigated. this was a cross-sectional study  on 376 participants, including   272 d...

lysozyme is a bactericidal enzyme whose structure and functions change in diabetes. chemical chaperones are small molecules including polyamines (e.g. spermine), amino acids (e.g. l-lysine) and polyols (e.g. glycerol). they can improve protein conformation in several stressful conditions such as glycation. in this study, the authors aimed to observe the effect of l-lysine as a chemical chaperon...

objective(s): organic cation transporter 3 (oct3) as a high-capacity transporter contribute to the metabolism of metformin. the present study was conducted to determine the genotype frequencies of the variant oct3-1233g>a (rs2292334) in patients with newly diagnosed type 2 diabetes (t2d) and its relationship with response to metformin. materials and methods: this study included 150 patients wit...

docosahexaenoic acid (dha), as an omega-3 fatty acid, in a natural ligand of peroxisome proliferator-activated receptors (ppars). regarding the combinative effects of nutrigenomics and nutrigenetics and due to the lack of in vivo studies conducted using natural ligands of ppars, we aimed to evaluate the effects of dha supplementation on vascular function, telomerase activity, and pparγ-lxrα-abc...