Introduction: In 3DCRT the number of therapeutic fields has dramatic impact on treatment results especially in stomach cancer. Traditionally, for radiotherapy of stomach cancer the therapeutic procedure was using two fields (AP- PA or AP Lateral with wedge) to achieve smooth and homogeneous dose distribution in tumor. But nowadays, adding lateral or oblique fields to aforement...

1 Radiotherapy Unit, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Largo Brambilla 3, 50134 Firenze, Italy 2 Department of Experimental Medicine, Sapienza University, 00161 Rome, Italy 3 RestorGenex Pharmaceuticals, Inc., 37 Neillian Crescent, Jamaica Plain, MA 02130, USA 4Laboratory of Radiobiology and Division of Radiotherapy, Department of Applied, Clin...

Gadolinium(III) texaphyrin (Gd-tex) was recently proposed as a radiosensitizing agent that combines preferential tumor uptake with detection of drug localization by magnetic resonance imaging (S. W. Young et al., Proc. Natl. Acad. Sci. USA, 93: 6610-6615, 1996). In view of the initial report on this compound, four radiobiology laboratories undertook independent efforts to further study radiosen...

Since the discovery of the damaging effects of ionizing radiations on cells, attempts have been made to increase the radiation curability of malig nant neoplasms by the simultaneous administra tion of various chemical agents. Three major ave nues of approach will be reviewed : (a) combining radiation with agents which themselves have antitumor properties in an attempt to gain a synergistic acti...

Small animal radiotherapy studies should be performed preferably on irradiators capable of focal tumor irradiation and healthy tissue sparing. In this study, an image guided small animal arc radiation treatment system (iSMAART) was developed which can achieve highly precise radiation targeting through the utilization of onboard cone beam computed tomography (CBCT) guidance. The iSMAART employs ...

One of the most important developments in radiobiology in recent years has been a change in the concept of the ability of the nervous system to withstand the effects of ionizing radiation. Until recently it had been generally believed that the tissue of the nervous system was especially resistant to radiation and that any kind of damage to it could occur only at extremely high radiation doses. ...