نتایج جستجو برای: tumor necrotizing factor alpha

تعداد نتایج: 1332861  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1991
M Lewis L A Tartaglia A Lee G L Bennett G C Rice G H Wong E Y Chen D V Goeddel

Complementary DNA clones encoding two distinct tumor necrosis factor receptors were isolated from a mouse macrophage cDNA library. The cDNA for murine tumor necrosis factor receptor type 1 (mTNF-R1) predicts a mature polypeptide of 425 amino acids that is 64% identical to its human counterpart, whereas the cDNA of murine tumor necrosis factor receptor type 2 (mTNF-R2) predicts a mature protein ...

Journal: :Critical care medicine 2006
Xiangru Lu Joel A Hamilton Ji Shen Theresa Pang Douglas L Jones Richard F Potter J Malcolm O Arnold Qingping Feng

OBJECTIVE Peripheral vascular surgery involving limb ischemia/reperfusion is associated with tumor necrosis factor-alpha production and an increased risk of cardiac complications. The objective of this study was to investigate the role of tumor necrosis factor-alpha in myocardial apoptosis and dysfunction following hindlimb ischemia/reperfusion. DESIGN Randomized perspective animal study. S...

Journal: :Cancer research 1987
B J Sugarman G D Lewis T E Eessalu B B Aggarwal H M Shepard

Tumor necrosis factors (TNFs) are a class of cytokines secreted by activated effector cells involved in host defense against tumor progression. Epidermal growth factor (EGF) and recombinant human transforming growth factor-alpha (rHuTGF-alpha) were shown to interfere with the in vitro antiproliferative effects of recombinant human tumor necrosis factor-alpha (rHuTNF-alpha) and -beta on a human ...

Journal: :The Journal of the Japanese Society of Clinical Cytology 1997

Journal: :iranian journal of allergy, asthma and immunology 0
nusrat saba institute of biomedical and genetic engineering, islamabad, pakistan and department of biochemistry, pirmehar ali shah arid agriculture university rawalpindi, pakistan osman yusuf the allergy and asthma institute of pakistan, islamabad, pakistan sadia rehman institute of biomedical and genetic engineering, islamabad, pakistan saeeda munir institute of biomedical and genetic engineering, islamabad, pakistan naghman bashir chest and medical specialist, medicsi, islamabad, pakistan atika mansoor institute of biomedical and genetic engineering, islamabad, pakistan

asthma is a chronic inflammatory and remodeling disorder of the airways, in which many cells, cellular elements, and cytokines play important roles. the role of tumor necrosis factor- α (tnf-α) in asthma is unclear in pakistani population. the aim of this study was to assess the relationship between tnf-α -308 polymorphism and asthma.polymorphism of tnf-α (g-308-a locus; rs 1800629) in 329 asth...

Journal: :Hypertension 2009
Carmine Vecchione Alessandro Frati Alba Di Pardo Giuseppe Cifelli Daniela Carnevale Maria Teresa Gentile Rosa Carangi Alessandro Landolfi Pierluigi Carullo Umberto Bettarini Giovanna Antenucci Giada Mascio Carla Letizia Busceti Antonella Notte Angelo Maffei Gian Paolo Cantore Giuseppe Lembo

Hypertension can lead to subarachnoid hemorrhage and eventually to cerebral vasospasm. It has been suggested that the latter could be the result of oxidative stress and an inflammatory response evoked by subarachnoid hemorrhage. Because an unavoidable consequence of hemorrhage is lysis of red blood cells, we first tested the hypothesis on carotid arteries that the proinflammatory cytokine tumor...

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