This study was aimed at investigating the immunologic relationship between cytokine production pattern and tuberculin negativity in patients with active Mycobacterium tuberculosis infection. After classifying patients by the extent of pulmonary involvement and the size of the tuberculin reaction, we evaluated the rate of cytokine positivity in peripheral blood to determine whether there is a ch...

In the present study, T-Spot.TB and the tuberculin skin test (TST) were compared in the screening of latent tuberculosis infection among silicotic patients. A conditional probability model was used to compare the potential clinical utilities of T-Spot.TB and TST performed on 134 silicotic subjects from December 1, 2004 to January 31, 2007. Data from a historical cohort were also reanalysed for ...

INTRODUCTION The tuberculin skin test is one of the most valuable tests for demonstrating tuberculous infection in both symptomatic and asymptomatic children. However, its application is often undermined by difficulties in interpretation of results arising from its low sensitivity and specificity. OBJECTIVES This review aimed to use the concept of induration distribution analysis to estimate ...

At a recent meeting of the National Association for the Prevention of Tuberculosis, a special plea was put forward for a wholesale examination of children of school age, with a view to discovering signs of existing latent tuberculous infection. There was general agreement that in such a routine examination the tuberculin test must play an important part. and it is the purpose of this paper to d...

BACKGROUND Tuberculosis is still an important problem in developing countries. The tuberculin skin test (TST) is used for the identification of latent tuberculosis (TB) infection. This study aimed to evaluate the TST results of healthy employees of different departments in chaharmahal province, Iran. MATERIALS AND METHODS This study was done on 1,424 healthy employees from 49 different depart...

purpose: to evaluate the diagnosis of intraocular tuberculosis (tb) with polymerase chain reaction (pcr) and to report 13 cases of presumed intraocular tb. methods: of 168 patients with uveitis, 13 patients (7.74%) had criteria for intraocular tb (tb group). thirteen patients with non-tb uveitis were randomly selected as the control group. samples for pcr were obtained from the aqueous humor. s...

Background & Objectives: Annually, many Muslims fast during the month of Ramadan worldwide. This practice has different favorable medical and physiological effects, such as improved serum lipid profile and blood glucose level due to changes in diet and sleep patterns. It has also been hypothesized that Ramadan fasting may affect the immune system. As reported, Ramadan fasting can influence the ...

OBJECTIVE To evaluate an interferon (IFN)-gamma release assay in diagnosing latent tuberculosis infection in pregnant adolescents and women at risk for exposure to Mycobacterium tuberculosis. METHODS This was a prospective study of women and adolescents receiving health care at Bellevue Hospital Outpatient Clinics in New York City. Each patient was assessed for M tuberculosis risk factors, ha...

easily differentiated from the BY normal contour and color of the A. R. MASTEN, M.D. s]dn Specific because without wheatridge, Colo. a pl.ece(]jng infection with tubercle bacilli no reaction will occur. Accurate because no other known combination of factors will give the same result. That is, a person cannot become sensitive to tuberculin by any means except a previous infection with tubercle b...