In many organisms the expression levels of each gene are controlled by the activation levels of known "Transcription Factors" (TF). A problem of considerable interest is that of estimating the "Transcription Regulation Networks" (TRN) relating the TFs and genes. While the expression levels of genes can be observed, the activation levels of the corresponding TFs are usually unknown, greatly incr...

Cardiovascular disease is the leading cause of morbidity and mortality in maintenance hemodialysis (MHD) patients. The Transonic (TRS; Transonic Systems, Ithaca, NY) device is frequently used for determination of cardiac output (CO) by an indicator dilution technique. The Task Force Monitor (TFM; CN Systems, Graz, Austria) has gained attention as noninvasive tool for continuous beat-to-beat ass...

For any class C of computable total functions satisfying some mild conditions, we prove that the following decision problems are complete for level Σ2 of the arithmetical hierarchy: (A) Deciding whether a term rewriting system (TRS for short) has runtime complexity bounded by a function in C. (B) Deciding whether a TRS has derivational complexity bounded by a function in C. In particular, the p...

Patients with schizophrenia often fail to respond to an initial course of therapy. This study systematically reviewed the societal and economic burden of treatment-resistant schizophrenia (TRS). Studies that described patients with TRS published 1996-2012 were included if they collected primary data on clinical, social, or economic outcomes. All studies were independently reviewed and extracted...

Tandem repeats (TRs) extensively exist in the genomes of prokaryotes and eukaryotes. Based on the sequenced genomes and gene annotations of 31 plant and algal species in Phytozome version 8.0 (http://www.phytozome.net/), we examined TRs in a genome-wide scale, characterized their distributions and motif features, and explored their putative biological functions. Among the 31 species, no signifi...

Thyroid hormone receptors (TRs) are members of the nuclear hormone receptor superfamily that act as ligand-dependent transcription factors. Here we identified the ten-eleven translocation protein 3 (TET3) as a TR interacting protein increasing cell sensitivity to T3. The interaction between TET3 and TRs is independent of TET3 catalytic activity and specifically allows the stabilization of TRs o...

The connuence property of ground (i.e., variable-free) term rewrite systems (TRS) is well-known to be decidable. This was proved independently in Dauchet et al. 1987; Dauchet et al. 1990] and in Oyamaguchi 1987] using tree automata techniques and ground tree transducer techniques (originated from this problem), yielding EXPTIME decision procedures (PSPACE for strings). Since then, and until las...

We propose the timescale-resolved spectroscopy (TRS) as a new method to combine the timing and spectral study. TRS is based on the time domain power spectrum and reflects the variable amplitudes of spectral components on different timescales. We produce the TRS with the RXTE PCA data for Cyg X-1 and studied the spectral parameters (the power law photon index and the equivalent width of the iron...

RATIONALE Up to one third of all schizophrenic patients are classified as having treatment-resistant schizophrenia (TRS). This subgroup faces remarkable medical and psychosocial damages, and pharmacotherapy is often limited due to nonresponse and/or side effects. Maintenance electroconvulsive therapy (M-ECT) might be effective in TRS. PATIENT CONCERNS We present a case of a 26-year-old male p...