DNA triple helices offer new perspectives toward oligonucleotide-directed gene regulation. However, the poor stability of some of these structures might limit their use under physiological conditions. Specific ligands can intercalate into DNA triple helices and stabilize them. Molecular modeling and thermal denaturation experiments suggest that benzo[f]pyrido[3, 4-b]quinoxaline derivatives inte...

In this study, by using X-ray powder diffraction profiles as blueprints, we successfully mapped the most probable molecular-level structural arrangement of the PMMA super-helix stereocomplexes through molecular dynamic simulations. Molecular-level resolution of the PMMA triple-helix supramolecule was not previously achievable by experimental methods. After constructing molecular models of stere...

The Riverside neighborhood bears multiple burdens of environmental harm. Running the gamut from groundwater contamination in subsurface waters to lead soils and dust paint particulate matter air highways industry, these insults harm physical, mental, economic well-being community. community has also faced an information gap where data was scarce, hard locate, sometimes wrong. Activists have lon...

Abstract University–industry (U–I) collaboration takes on many forms, from research services, teaching and training, to curiosity-led research. In the chemical industries, academic chemists generate new knowledge, address novel problems faced by industry, train future workforce in cutting-edge methods. this study, we examine dynamic structures of collaborative contracts grants between industry ...

The triple helix cooperation is in on-going development process Turkey. Government starting initiatives and supporting the industry universities with various financial incentives opportunities. Turkish Kazakh “research universities” have a special status, they are expected to produce knowledge that will be of great significance, innovation concrete outcomes products based upon creative innovati...

Society seems more complex molecular biology itself, depleting the model of the double helix so far valid model to explain the DNA – Desoxiribo Nucleid Acid, essential for understanding the structure and activity of the DNA and heredity. The innovation of the triple helix is now required to explain the relations between the academy, industry and government. Innovation has become the decisive ch...

Cooperative research centers (CRCs) are a significant and growing “triple helix-based” vehicle for promoting cross sector collaboration, knowledge and technology transfer and ultimately innovation. Although there is a growing social science literature on these organizational structures, the management and “best practice” portion of this literature have tended to emphasize success stories and to...