background: trichophyton verrucosum is a zoophilic fungus with a worldwide distribution. our aim was to investigate the proliferative effect of antigenic compounds of t. verrucosum on dermis fibro blasts and endothelial cells. methods: t. verrucosum was cultured in scc medium and was then transferred to a broth medium. surface antigens of this fungus were separated using the freeze and thaw met...

Background: Dermatophytes are the most common fungal agents causing superficial skin infections in worldwide. Species identification of these fungi is important for therapeutic and epidemiological apects. The purpose of this study was identification and epidemiology of dermatophytosis in patients referring to medical mycology laboratory of Razi hospital in Tehran, during 2014. Materials and Me...

Ethanol is an important industrial product. It can be degraded by microorganisms to use as sole source of carbon. Trichophyton mentagrophytes and Epidermophyton floccosum are most known species of dermatophytes. Their ability to degrade ethanol was detected. Low concentrations of ethanol enhanced two tested species of dermatophytes to grow on culture medium faster in absence of carbon source. A...

A 49-year-old male with Pneumocystis carinii pneumonia was seen at Bellevue Hospital in New York, N.Y. Sputum samples yielded cultures of Candida lusitaniae, Mycobacterium avium, and a filamentous fungus, Trichophyton fischeri. T. fischeri is a nonpathogenic fungus which resembles the dermatophyte Trichophyton rubrum. This is the first record of the species from U.S. sources. This case exemplif...

In fungi, ambient pH sensing involves the activation of the Pal/PacC signalling pathway. In the dermatophyte Trichophyton rubrum, pH-dependent secretion of keratinases, which are major virulence determinants, is affected by disruption of the pacC gene. Here, the transcription profiling of the genes coding for N- and O-linked mannosyltransferases, enzymes involved in protein glycosylation, was e...

We report the results of a study which aim was the mycological identification of specimens coming from patients included in a clinical trial. A total of 445 specimens from patients with clinical diagnosis of dermatomicosis were processed during 8 months (138 pityriasis versicolor, 28 cutaneous candidosis and 279 dermatophytosis). A 48% of pityriasis versicolor cultures were positive for Malasse...

Dermatophytes are keratinophilic molds that infect human hair, nails and skin. Diagnosis of dermatophytosis is based on morphological, serological and biochemical features. However, identification is difficult and laborious due to similarities between microorganisms. Thus, there is considerable interest to develop mycological diagnostic procedures based on molecular biology methods. In this stu...

The dermatophyte Trichophyton schoenleinii elaborates an extracellular collagenase which is specific for native collagen and gelatin and is separable from an enzyme which is active against Azocoll. The fungal enzyme differs from the bacterial collagenases in its acid pH and small molecular weight. In addition, the fungal enzyme is irreversibly inhibited by ethylenediaminetetraacetic acid, where...