In the title compound, C(19)H(15)N(3), the benzyl group is almost perpendicular to the triazole ring [dihedral angle = 80.64 (8)°], while the napthyl group makes an angle of 30.27 (12)° with the plane of the triazole ring. This conformation is different from the 1-benzyl-4-phenyl-1H-1,2,3-triazole analogue, which has the benzyl ring system at an angle of 87.94° and the phenyl group at an angle ...

Abstract Despite the remarkable progress in diagnostic and antifungal drugs research in past 10 years ,still complexity of the characteristics of patients continue to make the management of fungal infection is a great challenge .1,2,4-triazole compounds not only offer an interesting chemistry but also their various derivatives possesses diverse chemotherapeutic activity. The recent literatures ...

Heterocyclic 1,2,4-triazole derivatives possess unusually spacious potentiality as medicinal agents, agricultural chemicals, functional materials, ionic liquids, supramolecular catalysts as well as artificial enzymes and receptors for supramolecular recognition and biomimetic catalysis, and their various researches and developments have been being a quite rapidly developing and active highlight...

The nucleophilic ring opening of epoxy fatty esters was carried out using the amino-1,2,4-triazole to yield substituted derivatives of β-amino alcohol. The synthesis of the substituted beta amino alcohols has been achieved by refluxing equimolar quantities of long chain epoxy esters (epoxy fatty esters) and 4-amino-1,2,4-triazole in dichloromethane to yield following compounds, methyl 10-(4'-am...

Triazoles are an important class of compounds used as core molecule for the synthesis of many pharmaceutical drugs. The objective of the present research was to investigate the influence of biofield treatment on physical, spectral and thermal properties of 1,2,4-triazole. The study was performed in two groups, control and treatment. The control group remained as untreated, and biofield treatmen...

Derivatization of spirooxindole having triazole and ferrocene units was achieved by the [3 + 2] cycloaddition (32CA) reaction approach. Reacting respective azomethine ylide (AY) intermediate generated in situ with ethylene derivative produced novel asymmetric cycloadducts four contiguous carbons an overall high chemical yield excellent regioselectivity diastereoselectivity. X-Ray single-crystal...

In the current work, aromatic amines and alkyl halides have been converted to corresponding azides 2a‒d 4a-d by reaction with sodium nitrite azide respectively for halides. Then, dipropargyl ether derivative of D-mannose 8 has synthesized from diacetone mannose that obtained treatment (5) dry acetone in presence sulfuric acid. aldol condensation used prepare diol 7 diacetonide 6. The compound p...

The corrosion inhibiting properties of the new furan derivative 5-(furan-2-ylmethylsulfonyl-4-phenyl-2, 4-dihydro [1,2,4] triazole-3-thione in acidic solution (1.0 M HCl) were explored utilizing electrochemical, surface morphology (AFM), and quantum chemical calculations approaches. novel shows with an inhibitory efficiency value 99.4 percent at 150 ppm, carbon steel medium is effectively inhib...