Introduction The incidence of fungal infections is increasing at an alarming rate, presenting an enormous challenge to healthcare professionals. This increase is directly related to the growing population of immunocompromised individuals, resulting from changes in medical practice such as the use of intensive chemotherapy and immunosuppressive drugs. The most common fungal infections of humans ...

Introduction: Increased oxidative stress is widely accepted to be a factor in the development and progression of Alzheimer’s disease. Triazine derivatives possess a wide range of pharmacological activities including anti-oxidative and anti-in.ammatory actions. In this study, we aimed to investigate the possible protective effect of 3-thioethyl-5,6-dimethoxyphenyl-1,2,4-triazine (TEDMT) on H2O2-...

1,3,5-Triazine derivative are synthesized by replacement of chloride ions Cyanuric and showing promising biologically activity such as Antibacterial, Antifungal, Antimalarial, Antivirus, Anticancer that’s why interest researches on synthesis derivatives always in focused. The present study reported the 2,4,6-Trisubstituted Microwave mediated Method which gave desired result less time with highe...

The title compound, C(19)H(17)ClN(4), was obtained from the reaction of 3-chloro-5,6-diphenyl-1,2,4-triazine with isobutyronitrile in the presence of lithium diisopropyl-amide as an unexpected product of covalent addition of isobutyronitrile carbanion to the C-5 atom of the 1,2,4-triazine ring. The 2,5-dihydro-1,2,4-triazine ring is essentially planar (r.m.s. deviation = 0.0059 Å) and the 5- an...

Thesis Abstract Triazines represent a promising scaffold for cancer treatment due to their similarity the biologically active purine and pyrimidine systems. Besides, triazines annulated compounds exist in skeleton of numerous natural synthetic chemotherapeutic agents such as Azanucleosides (6-azacytosine 6-azauracil). Also, triazine derivatives proved display antiviral, anti-inflammatory, antim...