S2k-Guidelines of the German Society for Allergology and Clinical Immunology (DGAKI) in collaboration with the German Medical Association of Allergologists (AeDA), the German Professional Association of Pediatricians (BVKJ), the German Allergy and Asthma Association (DAAB), German Dermatological Society (DDG), the German Society for Nutrition (DGE), the German Society for Gastroenterology, Dige...

Rh(I) complexes of S-triazines were found very efficient towards the catalytic hydrogenation of alkenes, alkynes at normal pressure and at room temperature. Reduction of aromatic nitrocompounds, benzaldehyde and benzil were observed in appreciable amount only at high pressure and at high temperature. No diminished catalytic activity was observed even after 6-8 repeated catalytic runs. Profound ...

Regulated assemblies from vesicles to micelles based on 1,3-alternate oxacalix[2]arene[2]triazine amphiphilic molecules were reported. The vesicular entities were responsive to anions and followed the selectivity in the order NO3(-) > Cl(-) > Br(-) > ClO4(-), driven by cooperative anion-π interactions and hydrogen bonding.

O(6)-methylguanine-DNA methyltransferase plays vital roles in preventing induction of mutations and cancer as well as cell death related to alkylating agents. Mice defective in the MGMT: gene, encoding the methyltransferase, were used to evaluate cell death-inducing and tumorigenic activities of therapeutic agents which have alkylation potential. MGMT(-/-) mice were considerably more sensitive ...

A number of 3-alkyl analogues of the experimental antitumor drug mitozolomide [8-carbamoyl-3-(2-chloroethyl)imidazo|5,l-</l-l,2,3,5-tetni/iii-4Ct//Hmc| have been screened against murine tumors in vivo. Only the compounds with a 3-methyior 3-bromoethyl group possessed significant antitumor activity against the TLX5 lymphoma. The 3-methyl analogue, 8-carbamoyl-3-methylimidazo|5,1 -</]-!,2,3,5-tet...

A number of 3-alkyl analogues of the experimental antitumor drug mitozolomide [8-carbamoyl-3-(2-chloroethyl)imidazo|5,l-</l-l,2,3,5-tetni/iii-4Ct//Hmc| have been screened against murine tumors in vivo. Only the compounds with a 3-methyior 3-bromoethyl group possessed significant antitumor activity against the TLX5 lymphoma. The 3-methyl analogue, 8-carbamoyl-3-methylimidazo|5,1 -</]-!,2,3,5-tet...