BACKGROUND Bipolar disorder is a significant cause of morbidity and mortality. Although existing treatments are effective, there is often a substantial delay before diagnosis and treatment initiation. We sought to investigate factors associated with the delay before diagnosis of bipolar disorder and the onset of treatment in secondary mental healthcare. METHOD Retrospective cohort study using...

BACKGROUND Delay in seeking treatment at the hospital is a major challenge in current Buruli ulcer control; it is associated with severe sequelae and functional limitations. Choosing alternative treatment and psychological, social and practical factors appear to influence delay. Objectives were to determine potential predictors for pre-hospital delay with Leventhal's commonsense model of illnes...

OBJECTIVES To examine the delay in presentation, diagnosis, and treatment of malignant spinal cord compression and to define the effect of this delay on motor and bladder function at the time of treatment. DESIGN Prospective study of all new patients presenting to a regional cancer centre with this condition. SETTING Regional cancer centre. SUBJECTS 301 consecutive patients. MAIN OUTCOM...

BACKGROUND Currently, there is limited data on the risk factors associated with treatment delay in tuberculous meningitis (TBM). This study aimed to assess the duration of delay in the treatment TBM and to investigate its determinants. METHODS During the period from September 2009 to February 2016, a retrospective cohort study of consecutive TBM patients admitted to our hospital was conducted...

Delay in the delivery of treatment for gynaecological cancers has been previously investigated. 2 In some cases, the delay reflects the illness behaviour of women; in others, it was inherent in the system for delivering health care. Few studies have linked delay in treatment with survival, although a study from Israel found that survival from endometrial cancer was not affected by a delay in tr...

this article proposes a direct method for solving three types of integral equations with time delay. by using operational matrix of integration, integral equations can be reduced to a linear lower triangular system which can be directly solved by forward substitution. numerical examples shows that the proposed scheme have a suitable degree of accuracy.

BACKGROUND Pulmonary tuberculosis continues to increase due to late patient presentation. The study was conducted at a chest clinic of a general hospital in Lagos, Nigeria, to investigate patterns of delays before treatment amongst tuberculosis patients. METHODS Longitudinal recruitment using a health worker administered protocol to determine time interval from onset of symptoms to initiation...