(AD). Although physical exercise and AD have received attention in the scientific literature, the mechanism through which treadmill exercise may impact the brain insulin signaling of AD has not been elucidated. This study aimed to evaluate the neuroprotective effects of treadmill exercise on apoptotic factors (Bcl-2/Bax ratio, caspase-3), HSP70, COX-2, BDNF and PI3-K/Akt signaling pathway in th...

To compare the hemodynamic and gas exchange responses of ramp treadmill and cycle ergometer tests with standard exercise protocols used clinically, 10 patients with chronic heart failure, 10 with coronary artery disease who were asymptomatic during exercise, 11 with coronary artery disease who were limited by angina during exercise and 10 age-matched normal subjects performed maximal exercise u...

50 patients with diabetes were compared with 20 non-diabetic subjects, with respect to the prevalence of silent myocardial ischemia, by means of treadmill exercise testing. Results of treadmill exercise testing showed ischemia in 14 of the 50 diabetic patients (mean age 49.2 * 1.3) and in 2 of 20 non-diabetic control subjects (mean age 49 * 6 y.) (28%VS lo%, P < 0.05). Diabetics with “positive ...

Therapeutic exercise is an integral component of the rehabilitation of patients who have suffered a stroke. The objective of the present study was to use immunohistochemistry to investigate the effects of post‑ischemic exercise on neuronal damage or death and gliosis in the aged gerbil hippocampus following transient cerebral ischemia. Aged gerbils (male; age, 22‑24 months) underwent ischemia a...

This study assesses the safety of and physiologic responses to maximal repetition, dynamic, resistive weight lifting at 40, 60, 80 and 100% of maximal voluntary contraction compared with aerobic exercise using a maximal treadmill exercise test. Twelve men with coronary artery disease exercised to fatigue at 4 stations (overhead press, biceps curl, quadriceps extension and supine press). The ele...

[Purpose] The purpose of this study was to evaluate the kinematics of the ankle in the lunge to estabilish effectiveness of an ankle stretching orthosis (ASO) on the ankle dorsiflexion range of motion (ROM) of individuals with limited dorsiflexion ROM. [Subjects and Methods] Forty ankles with decreased dorsiflexion ROM of 20 participants were evaluated in this study. After wearing the ASO, part...

In the present study, the effect of treadmill exercise on short-term memory, apoptotic neuronal cell death, and cell proliferation in the hippocampal dentate gyrus following transient global ischemia in gerbils was investigated. Step-down inhibitory avoidance task, terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay, and immunohistochemistry for caspase-3 and 5-b...

[Purpose] This study investigated the effects of inclined treadmill walking on pelvic anterior tilt angle, hamstring muscle length, and back muscle endurance of seated workers with flat-back syndrome. [Subjects] Eight seated workers with flat-back syndrome who complained of low-back pain in the L3-5 region participated in this study. [Methods] The subjects performed a walking exercise on a 30° ...

OBJECTIVE The aim of this study was to explore whether attentional demands are involved in gait improvements in Parkinson disease (PD) patients when they walk on a treadmill. DESIGN Nineteen individuals with idiopathic PD and 19 age-matched healthy controls participated in this study. Participants walked on a treadmill and on overground under single task (walk only) and dual task (walk perfor...

Twenty-five patients had myocardial blood flow reserve determinations (percentage increase in myocardial blood flow with stress), treadmill exercise tests and coronary and bypass cineangiography preand postaortocoronary bypass surgery. Twenty of the patients had the postoperative studies performed three months after operation, three at two months and two at five and six months, respectively. El...