Traumatic brain injury (TBI) is described by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. The use of human stem cells and self-assembling peptide scaffolds suggest huge potential for application in the treatment of TBI. In the present study, we surveyed the beneficial effec...

context traumatic brain injury (tbi) is a leading cause of death, disability, and resource consumption per year. there are two kinds of brain injury in tbi, primary and secondary injuries. primary injury refers to the initial physical forces applied to the brain at the moment of impact. secondary injury occurs over a period of hours or days following the initial trauma and results from the acti...

BACKGROUND Traumatic brain injury (TBI) is in the developed countries the most common cause of death and disability in childhood. AIM The purpose of this study is to estimate the incidence of TBI for children and young people in an urbanised region of the Netherlands and to describe relevant characteristics of this group. METHODS Patients, aged 1 month - 24 years who presented with traumati...

OBJECTIVES Provide test-retest reliability (>5 months) of the Ohio State University Traumatic Brain Injury Identification Method modified for use as a computer-assisted telephone interview (CATI) to capture traumatic brain injury (TBI) and other substantial bodily injuries among a representative sample of noninstitutionalized adults living in Colorado. DESIGN Four subsamples of 50 individuals...

Background and Aim: We aimed to determine the prognostic imaging and clinical markers of chronic Post-Traumatic Sleep-Wake Disorders (PTSWDs) with a special focus on the early cognitive and executive dysfunctions following Traumatic Brain Injury (TBI). The prevalence rate of Post-Traumatic Psychiatric Disorders (PTPDs) in various sleep disorders was also investigated. Methods and Materials/Pat...

main goal in the management of patients with severe traumatic brain injury (tbi) is control of intracranial pressure (icp). decompressive craniectomy is an accepted technique for control of refractory intracranial hypertension in patients with severe tbi. because of high complication rate after decompressive craniectomy, new techniques such as basal cisternostomy have developed. we herein repor...

Although post-traumatic stress disorder (PTSD) and traumatic brain injury (TBI) are categorized as separate and discrete disorders, the boundary between them is sometimes indistinct. Their separation is based on the assumption that PTSD results primarily from psychological stress, while TBI is the consequence of an identifiable injury to the brain. This distinction is based on an antiquated pol...

Insulin-like growth factors (IGF) are potent neurotrophic and neurorepair that were recently proposed as biomarkers of traumatic brain injury (TBI) associated psychiatric comorbidities, in particular post-traumatic stress disorder (PSTD). We tested the hypothesis IGF system is differentially deregulated acute early chronic stages TBI, under stress. Plasma IGF1 IGF2 levels evaluated mice 3 weeks...

‘Severe’ Traumatic Brain Injury (TBI) survivors are likely to be hospitalised and experience Post Amnesia (PTA): a transient state of confusion, disorientation memory loss, until the return continuous memory. Survivors often distressing ‘islands’ during PTA, this can exacerbate psychological deterioration lead additional poor outcomes if left untreated. The literature for neuropsychological reh...

OBJECTIVE Following traumatic brain injury (TBI), brain tissue that surrounding the regional primary lesion is known as traumatic penumbra; this region may undergo secondary injury and is considered to have the potential to recover. This review aimed to reveal the existence and significance of traumatic penumbra by analyzing all relevant studies concerning basic pathologic changes and brain ima...