BACKGROUND Upper tract transitional cell carcinomas (TCC) are uncommon and aggressive tumours. There are a number of surgical approaches to manage this condition including open radical nephroureterectomy and laparoscopic procedures. OBJECTIVES To determine the best surgical management option for upper tract transitional cell carcinoma. SEARCH STRATEGY A sensitive search strategy was develop...

Approximately 70% to 85% of patients with transitional cell carcinoma of the bladder present with tumors that are confined to the mucosa or submucosa. Recent articles have proposed that these tumors should be classified in one major group and treated in a similar fashion. Although a number of molecular and biologic markers can be used to segregate more aggressive tumors from those with little m...

background & objectives:  cd10 is a cell surface enzyme with metalloendopeptidase activity, also known as common acute lymphoblastic leukaemia antigen, which mainly serves as a marker for acute lymphoblastic leukemia (all). to date and to the best of our knowledge, only few comparative immunohistochemical studies have assessed cd10 expression in cutaneous epithelial neoplasms. our goal was ...

OBJECTIVE The aim of our study was to determine whether there is an increased incidence of urothelial cancer, especially transitional cell carcinoma (TCC), in uremic patients on dialysis. METHODS Retrospective chart analyses were completed for 1,910 uremic patients undergoing maintenance dialysis between January 1987 and December 1997. The incidence of urinary tract cancer was assessed. Only ...

Urine samples from the greatest proportion of the numerical workload of most clinical microbiology laboratories. During the screening by microscopy, atypical cells were detected which did not conform to the normal cellular morphology found in urinary deposits. These specimens were referred to the Department of Cytopathology for a second opinion. From these referrals a small but significant numb...

A case of transitional cell carcinoma of the kidney associated with long-term phenacetin intake is described and the practical implications discussed.

Primary urethral carcinoma is a rare malignancy with an annual age-adjusted incidence rate of 1.5 per million in females in the U.S. The three main histologic subtypes include transitional-cell carcinoma, squamous-cell carcinoma, and adenocarcinoma. Of these, adenocarcinoma is the least common. Female urethral carcinomas are aggressive neoplasms with a generally poor prognosis. We report a case...

The thyroid gland is a rare site for cancer metastasis. We report a 75-year-old man who was referred with a history of hematuria and generalized bone pain for the past few months. He had a past history of partial left lobe thyroidectomy for follicular adenoma. Subsequently he was referred for a thyroid mass and a subtotal thyroidectomy showed a poorly-differentiated carcinoma. On the latest adm...

Urothelial carcinoma developing in orthotopic ileal neobladder is an extremely rare entity. Fewer than 10 cases have been reported in the literature describing urothelial carcinoma recurrence in orthotopic ileal neobladder. We report a case of transitional cell carcinoma recurrence in orthotopic ileal neobladder after 11 years of surgery.

Following cystectomy for transitional cell carcinoma a 63 year old woman developed recurrent tumours in the upper urinary tract and ileal conduit, suggesting that malignant transitional cells can auto-implant in ileal epithelium. This phenomenon has not been previously reported. We illustrate the value of retrograde urogram via an ileal conduit following cystectomy for cancer.