OBJECTIVE To explore opioid use by aged care facility residents before and after initiation of transdermal opioid patches. DESIGN A cross-sectional cohort study, analysing pharmacy data on individual patient supply between 1 July 2008 and 30 September 2013. SETTING Sixty residential aged care facilities in New South Wales. PARTICIPANTS Residents receiving an initial opioid patch during th...

OBJECTIVE To review current knowledge of the efficacy, safety and cost of transdermal nicotine therapy for smoking cessation. DATA SOURCES AND STUDY SELECTION 1. Published and unpublished reports of randomised, double-blind trials of at least 12 weeks' duration, in smokers motivated to cease smoking, identified by a search of the MEDLINE database, article and book bibliographies, Current cont...

OBJECTIVES To determine the risk of stroke associated with oral and transdermal routes of administration of hormone replacement therapy. DESIGN Population based nested case-control study. Setting About 400 general practices in the United Kingdom contributing to the General Practice Research Database. Participants Cohort of all women in the database aged 50-79 years between 1 January 1987 and ...

This study evaluated the feasibility of coating formulated recombinant human growth hormone (rhGH) on a titanium microneedle transdermal delivery system, Zosano Pharma (ZP)-hGH, and assessed preclinical patch delivery performance. Formulation rheology and surface activity were assessed by viscometry and contact angle measurement. rhGH liquid formulation was coated onto titanium microneedles by ...

Transdermal patches loaded with pravastatin was previously characterized in another published study by Serrano-Castañeda et al; 2015. These transdermal patches (TP) were generated by the plate casting technique, the in vitro percutaneous absorption studies of TP were evaluated for three different formulations of TP with different quantities of Pluronic F-127 (PF-127): i) without PF-127 (TP W), ...