Eukaryotic genes generate multiple RNA transcript isoforms though alternative transcription, splicing, and polyadenylation. However, the relationship between human transcript diversity and protein production is complex as each isoform can be translated differently. We fractionated a polysome profile and reconstructed transcript isoforms from each fraction, which we term Transcript Isoforms in P...

During transcript elongation in vitro, backtracking of RNA polymerase II (RNAPII) is a frequent occurrence that can lead to transcriptional arrest. The polymerase active site can cleave the transcript during such backtracking, allowing transcription to resume. Transcript cleavage is either stimulated by elongation factor TFIIS or occurs much more slowly in its absence. However, whether backtrac...

This article explores comic-strip-inspired graphic transcripts as a tool to present conversational video data from informal multiperson conversations in signed language, specifically Norwegian Sign Language (NTS). The interlocutors’ utterances are represented English translations speech bubbles rather than glossed or phonetically transcribed NTS, and the discusses advantages disadvantages of th...

Abstract This article is a transcript of an interview with the previous editor-in-chief Philosophy Management (2010–2017) . It discusses his career, use and hopes for field philosophy management, leading journal.

This is an edited transcript of a conversation held in Thurloe Sq, London, on 25 July 2020. Peter Wilson’s exhibition ‘Indian Summer and Thereafter’ had opened at Betts Project the previous evening...