Phencyclidine [PCP, Sernyl#{174}, 1-(1-phencyclohexyl) piperidine] is a potent analgesic originally developed as an intravenous anesthetic. Deemed unsuitable for human use, it is currently marketed legitimately as a primate tranquilizer. The illegitimate use of phencyclidine has increased drastically throughout the United States since its “discovery” on the West Coast by the so-called drug cult...

BACKGROUND Leonotis nepetifolia Linn (Lamiaceae) is used in traditional medicine for its calming (tranquilizing) effects. The aim of this study was to determine whether there is any scientific justification for this use. To achieve this purpose, we investigated the behavioural effects of the methanol extract of Leonotis nepetifolia stem (37.5, 75 and 150 mg/kg) in mice. METHODS Acute toxicity...

The ability to inject wild animals from a distance using remote drug delivery systems (RDDS) is one of the most effective and humane practices in wildlife management. Several factors affect successful administration drugs RDDS. For example, temperature-dependent viscosity change aqueous (Newtonian) or water-in-oil emulsion (non-Newtonian) fluids, commonly used tranquilizer adjuvant-based vaccin...

Background and objectives: Many Nepeta species have been commonly used in Iranian folk medicine as tranquilizer, relaxant, carminative and restorative tonic for nervous and respiratory disorders. Inflammation is a problem in many diseases and has an important role in brain function that can cause neurodegenerative disorders. Inflamed glial cells can exacerbate neurodegenerative disease...

Dvorak M.: Growth, Metabolic and Adrenocortical Effects of Single and Repeated Administration of Diazepam in Piglets. Acta vet. Brno, 49, 1980: 177-186. Diazepam was injected as a single i/m dose to suckling piglets of two groups on the 2nd day after birth at 0.5 or 1.0 mgjkg body mass. In two other groups of pigs weaned at 4 weeks of age it was injected at 0.5 mgjkg body mass or fed for 14 day...

objective: pimpinella anisum (p. anisum) has different pharmacological properties such as anticonvulsant, analgesic, tranquilizer, antidepressant and anti-anxiety effects. in this study the antidepressant-like effect of aqueous and ethanolic extracts of p. anisum fruit in mice was investigated. materials and methods: forced swimming test (fst) and tail suspension test (tst) were used to determi...

Objective: Pimpinella anisum (P. anisum) has different pharmacological properties such as anticonvulsant, analgesic, tranquilizer, antidepressant and anti-anxiety effects. In this study the antidepressant-like effect of aqueous and ethanolic extracts of P. anisum fruit in mice was investigated. Materials and Methods: Forced swimming test (FST) and tail suspension test (TST) were used to determ...

cal – chest XP and CT revealed no lesion affecting the recurrent and/or vagus nerves. The family’s consent to perform tracheotomy was not obtained. At the age of 89, he was admitted to our hospital with pyrexia. On admission, neurological examination revealed new findings including right-sided dominant rigidity and Myerson’s sign. Resting tremor was absent. He showed severe dementia (MMSE 0/30)...

In 16 burn patients, mean values for serum T4 and T3, their T3 uptake-derived free indices (FT4I and FT3I) and dialysis-derived free concentrations (FT4 and FT3) were depressed (all P less than 0.001) compared to respective means in 13 normal subjects. In the patients, the free hormone indices were relatively more depressed below control values than were the free hormone concentrations. However...