نتایج جستجو برای: traditional cardiovascular biomarkers

تعداد نتایج: 583640  

Journal: :Circulation 2012
Thomas J Wang Kai C Wollert Martin G Larson Erin Coglianese Elizabeth L McCabe Susan Cheng Jennifer E Ho Michael G Fradley Anahita Ghorbani Vanessa Xanthakis Tibor Kempf Emelia J Benjamin Daniel Levy Ramachandran S Vasan James L Januzzi

BACKGROUND Biomarkers for predicting cardiovascular events in community-based populations have not consistently added information to standard risk factors. A limitation of many previously studied biomarkers is their lack of cardiovascular specificity. METHODS AND RESULTS To determine the prognostic value of 3 novel biomarkers induced by cardiovascular stress, we measured soluble ST2, growth d...

Journal: :Circulation 2006
Jean-Claude Tardif Therese Heinonen David Orloff Peter Libby

Cardiovascular biomarker research efforts have resulted in the identification of new risk factors and novel drug targets, as well as the establishment of treatment guidelines. Government agencies, academic research institutions, diagnostic industries, and pharmaceutical companies all recognize the importance of biomarkers in advancing therapies to improve public health. In drug development, bio...

Journal: :Thrombosis and haemostasis 2009
Wouter J Eijgelaar Sylvia Heeneman Mat J A P Daemen

The term 'vulnerable plaque' is used to refer to the lesions that are prone to rupture and may cause life-threatening events like acute coronary syndrome or stroke. The study of the vulnerable plaque phenotype and its detection has attracted increasing interest over the past decades. During this time, there have been some remarkable transitions in the paradigm on methods to identify patients at...

2012
Xiaolun Sun Zhenquan Jia

Cardiovascular diseases are the most prominent circulation disorders around the world. Biomarkers are characteristic biological properties that can be objectively measured as an indicator to evaluate a variety of health or disease characteristics. Cardiac biomarkers are a valuable tool for assessing the pathogenesis and diagnosis of cardiovascular diseases. In this review, we will focus on the ...

2018
Maxime Cournot Elena Burillo Pierre‐Jean Saulnier Cynthia Planesse Elise Gand Michaela Rehman Stéphanie Ragot Philippe Rondeau Aurélie Catan Marie‐Paule Gonthier Eva Feigerlova Olivier Meilhac Samy Hadjadj

BACKGROUND Despite pathophysiological relevance and promising experimental data, the usefulness of biomarkers of oxidative stress for cardiac risk prediction is unclear. The aim of our study was to investigate the prognostic value of 6 biomarkers exploring different pathways of oxidative stress for predicting adverse cardiovascular outcomes in patients with type 2 diabetes mellitus beyond estab...

Journal: :Applied sciences 2021

Heart failure (HF) and type 2 diabetes mellitus (T2DM) have a synergistic effect on cardiovascular (CV) morbidity mortality in patients with established CV disease (CVD). The aim of this review is to summarize the knowledge regarding discriminative abilities conventional novel biomarkers T2DM HF or at higher risk developing HF. While biomarkers, such as natriuretic peptides high-sensitivity tro...

Journal: :Journal of the American College of Cardiology 2010
Claire L Heslop Jiri J Frohlich John S Hill

OBJECTIVES We evaluated the relative and combined value of oxidative stress biomarkers for predicting cardiovascular mortality in patients undergoing selective coronary angiography. BACKGROUND Oxidative stress participates in all stages of cardiovascular disease, from lipoprotein modification to plaque rupture, and biomarkers of oxidative stress predict development of coronary artery disease ...

abdol-Naser Mohebbi Afshin Jafari Dehkordi, Shima Balali Dehkordi

BACKGROUND: Cardiovascular system is a very importantorgan that plays a vital role in tissue function. In farm animals,the growth and high milk production depends on function ofcardiovascular system. OBJECTIVES: Cardiovascular health inhigh and low-yielding dairy cows was investigated. METHODS:Fifty 4-year-old high- yielding Holstein dairy cows and fifty 4-year-old low- yielding Holstein dairy ...

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