نتایج جستجو برای: toxin conjugate
تعداد نتایج: 92714 فیلتر نتایج به سال:
در این پروژه آنالیز مسئله انتقال حرارت مزدوج(conjugate) برای جریان آرام توسعه یافته سیال در داخل یک لوله طولانی که قسمت محدودی از طول آن در معرض شار حرارتی ثابت قرار گرفته و بقیه طول آن عایق بندی شده، با در نظر گرفتن اثرات هدایت محوری در سیال و هدایت دو بعدی در لوله مورد بررسی قرار گرفته است .
manufacturing new hepatitis b virus vaccines, specifically by the use of nanoparticles, is of high global interest. in this paper, a new biocompatible and biodegradable structure of nano-sized hepatitis b virus’ surface antigen (hbsag) was generated by conjugation with dendrimers, a low cost biodegradable and biocompatible polymer. the physicochemical properties of the conjugate were characteri...
miRNAs as one of the potential therapeutic agents have been recently considered for cancer treatment. AS1411 (aptNCL) is a DNA aptamer specifically binding to nucleolin protein on the cancer cell surface with antiproliferative effect. The aim of the study was to develop a conjugate consisted of aptNCL (as targeted delivery of therapeutic agent) and miRNA let-7d (as a tumor suppressor) using two...
Abstract Cell deletion approaches to pain directed at either the primary nociceptive afferents or second-order neurons are highly effective analgesic manipulations. Second-order spinal neurons expressing the neurokinin 1 (NK1) receptor are required for the perception of many types of pain. To delete NK1+ neurons for the purpose of pain control, we generated a toxin–peptide conjugate using DTNB-...
the generalization of p-frame in banach spaces is considered in this paper. the concepts of an $tilde{x}$-frame and a system conjugate to $tilde{x}$-frame were introduced. analogues of the results on the existence of conjugate system were obtained. the stability of $tilde{x}$-frame having a conjugate system is studied.
Peptide-protein conjugates are useful tools in different fields of research as, for instance, the development of vaccines and drugs or for studying biological mechanisms, to cite only few applications. N-Succinimidyl carbamate (NSC) chemistry has been scarcely used in this area. We show that unprotected peptides, featuring one lysine residue within their sequences, can be converted in good yiel...
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