OBJECTIVES To determine effects of selectin inhibitor TBC1269 on neutrophil infiltration, and neutrophil-associated injury during pneumonia induced by Mannheimia haemolytica and concentration of antimicrobial anionic peptide (AAP) in bronchoalveolar lavage fluid (BALF) as well as antimicrobial activity of BALF from healthy (control) neonatal calves, neonatal calves with M haemolytica-induced pn...

p53, a tumor suppressor protein and a transcription factor, is capable of inhibiting the growth of tumor cells by eliciting either cell-cycle arrest or apoptosis through a cascade of events. p53 binds sites within the promoters of several genes that conform to a sequence commonly defined as the consensus site. In more than 50% of cancer cases, the p53 gene has been found to be mutated and the p...

Clostridium thermocellum has emerged as a leading bioenergy-relevant microbe due to its ability to solubilize cellulose into carbohydrates, mediated by multicomponent membrane-attached complexes termed cellulosomes. To probe microbial cellulose utilization rates, it is desirable to be able to measure the concentrations of saccharolytic enzymes and estimate the total amount of cellulosome presen...

Reference 1. Theilacker C, Diederich A-K, Otto A, Sava IG, Wobser D, Bao Y, et al. (2015) Enterococcus faecalis Glycolipids Modulate Lipoprotein-Content of the Bacterial Cell Membrane and Host Immune Response. PLoS ONE 10(7): e0132949. doi: 10.1371/journal.pone.0132949 PMID: 26172831 Fig 3. Stimulation of TNF-α production in RAW 264.7 mousemacrophages by lipoprotein-enriched cell membrane fract...

A 60-day trial with six diets (three different protein levels × two different lipid levels) containing 30, 35 and 40% protein with 10 and 15% lipid levels was conducted to determine the optimum dietary protein to lipid ratio and effects on growth performance and hematological indices of Aspikutum, Leuciscus aspius female×Rutilus frisii male. Two hundred and fifty two fish (31.2±0.4 g; mean±SEM)...

BACKGROUND Our previous study has recently shown that plasma heme oxygenase-1 (HO-1), a stress-responsive protein, is elevated in individuals with type 2 diabetes. The current study aimed to examine the association between plasma HO-1 concentration and impaired glucose regulation (IGR) in non-diabetic individuals. METHODS We conducted a case-control study including a total of 865 subjects (26...