A reliable method for the determination of total liver iron in formalin-fixed, paraffin-embedded tissue is presented. The correlation with total liver iron in fresh tissue is good (r = 0.92). Material, which is processed routinely in the pathological anatomical department and stored in the archives, can be used for a quantitative iron determination for clinical or research purposes.

BACKGROUND Banana is a staple food in many regions with high iron deficiency and may be a potential vehicle for iron fortification. However, iron absorption from bananas is not known. OBJECTIVE The objective of this study was to evaluate total iron absorption from raw and cooked bananas. DESIGN Thirty women (34.9±6.6 years) from rural Mexico were randomly assigned to one of two groups each ...

Several life-threatening complications of the common disorder sickle cell disease require management with red blood cell transfusions and, hence, long-term iron-chelating therapy. The efficacy of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1) has not previously been determined in patients with sickle cell disease. We compared the efficacy of L1 to that of standard-dose subcutaneo...

Introduction Intravenous iron administration in patients treated by haemodialysis for end stage renal disease can exacerbate oxidative stress by increasing the level of free redox active iron. A way to reduce the impact of iron on oxidative stress in haemodialysis patients may be the administration of iron through arterial extracorporeal circuit. Objective The aim of our study was to compare th...

The serum transferrin concentration is usually overestimated when assessed as total iron binding capacity, because iron binds not only to transferrin but also, non-specifically, to other serum proteins [l-3]. Transferrin concentration can be measured directly by immunochemical methods including: radial immunodiffusion [ 1,2,4-61, immunonephelometric assay [6,7] and immunoturbidimetric assay [8,...

BACKGROUND Heme and total iron, present in meat, have been hypothesized to promote carcinogenesis. Few prospective studies have examined the associations between intakes of heme and total iron, types of meat, and endometrial cancer risk. OBJECTIVE We evaluated the associations between intakes of heme and total iron, types of meat, and risk of endometrial cancer in a large cohort of women. D...

The aim of the present study was to determine changes in body iron storage in adult dogs following phlebotomy. We performed repeated phlebotomies by removing 1% body weight (approximately 10% of the total blood volume) weekly for a total of 12 times using adult beagle dogs without an iron-restricted diet. After treatment, stored iron was decreased, as demonstrated by gradual reductions in serum...

iron oxide is an important biological agent that has a key role in medical processes; however, the mechanism whereby it provides iron for human and animal cells and its biological uses remains unclear. we aimed to evaluate the effects of oral iron oxide on serum iron status and compare the results with those of iron sulfate as a reference salt. fifteen adult rabbits were divided into 3 groups o...

iron is an essential microelement for plant growth. low content of organic matter and excess application of phosphate fertilizer in soils can be affected on availability of iron. in this study the effect of iron, phosphorus and organic matter on growth and iron uptake of mays was evaluated. a greenhouse experiment was conducted with two levels of cattle manure (0 and 1 %), three levels of phosp...

natural organic wastes contain considerable amounts of nutritional elements. the availability and uptake of nutrient elements in soil) especially in alkali and calcareous soils) increase due to high content of organic matter, and reduce the micro-elements deficiencies. organic wastes have pathogenic contaminations that come from waste type and transmitted by microorganisms such as bacteria, fun...