When users of information systems judge the relevance of search results, diverse criteria beyond topical relevance come into play. In this paper, we introduce the doctoral project Relevance Clues, which, through an experimental design, seeks to gain significant knowledge on the criteria by which users make relevance judgments.

Starting from a few topical astrophysical questions which require the knowledge of the age of Pop I stars, we discuss the needed precision on the age in order to make progresses in these areas of research. Then we review the effects of various inputs of the stellar models on the age determination and try to identify those affecting the most the lifetimes of stars.

Psoralen photochemotherapy [psoralen ultraviolet A (PUVA)] plays an important part in dermatological therapeutics, being an effective and generally safe treatment for psoriasis and other dermatoses. In order to maintain optimal efficacy and safety, guidelines concerning best practice should be available to operators and supervisors. The British Photodermatology Group (BPG) have previously publi...

Alitretinoin is a unique retinoid authorised for the treatment of adults with severe chronic hand eczema (CHE) refractory to potent topical steroids. The most common adverse events (AEs) were typical class effects of oral retinoids including headache, flushing and skin disorders. To our knowledge, there are no cases of sensitization to alitretinoin reported in literature. We present a case of s...

Description: Integrating SAMPLE PREPARATION conference webcast, a part of the Knowledge Foundation’s Detection Technologies Conference Series an internationally recognized meeting for experts in sample preparation technologies for detection, identification and analysis of biological and chemical agents and threats, will explore the latest R&D developments as well as ready-to-market technologies...

Purpose To report the first sequential cross-over treatment with the longest ophthalmic follow-up in a case of X-linked juvenile retinoschisis (XLRS) successfully treated with topical dorzolamide. Observations A healthy 34 year-old man presented with one month history of decreased visual acuity in his left eye. Funduscopy was significant for a blunted and cystoid-like foveal reflex in both ey...

There has been an increasing focus on development of new routes of drug administration to provide tailored treatments for patients, without decreasing efficacy of analgesia, in proportion to the progression of the knowledge of pain mechanisms. While acute pain acts as an alarm, chronic pain is a syndrome requiring meticulous selection of analgesic drugs of high bioavailability for long-term use...

INTRODUCTION During cataract surgery under regional (retrobulbar, peribulbar or sub- Tenon's) or topical anaesthesia, many patients experience a variety of visual sensations in their operated eye intraoperatively. Between 3% and 16.2% of patients are frightened by their intraoperative visual experiences, which may increase the risk of intraoperative complications and affect patients' satisfacti...