INTRODUCTION Topicals are a mainstay in psoriasis vulgaris treatment and are used concomitantly even in patients receiving systemic therapy. Patient acceptance of topical treatment can impact adherence and, consequently, real-life effectiveness. This study aimed to identify patient preferences for topical treatment attributes and to evaluate patient acceptability of topical treatments. METHOD...

In this case report a patient with therapeutically recalcitrant erythrodermic psoriasis is presented. After various attempts with several major therapies in this patient, the first substantial improvement was achieved using the combination of cyclosporine and calcipotriol, followed by the combination of UVB and calcipotriol. The therapeutic options for severe psoriasis are discussed, and since ...

Background: Calcipotriol/betamethasone dipropionate ointment has been successfully used in psoriasis vulgaris of active stage. However, the data of stationary stage was lack. Aims: To investigate the optimal regime of calcipotriol/betamethasone dipropionate ointment on psoriasis vulgaris of stationary stage. Methods: Patients were randomized into 3 groups, with calcipotriol/betamethasone ointme...

A 66-year-old male suffered from painful pustular eruptions of acrodermatitis continua of Hallopeau on bilateral thumbs for about 2 years, with associated nail dystrophy and markedly disabled manual skills. Initial treatment with topical corticosteroids, tars and calcipotriol failed to improve the acral lesions. Dapsone therapy began at a dose of 200 mg / day, which cleared the acral lesions wi...

Although uncommonly diagnosed, clear cell acanthoma represents an original source of speculative interest for dermatologists. Due to its clinical variability, it is often only recognized accidentally after histology. Dermoscopy has improved the reliability of clinical diagnosis of typical clear cell acanthoma thanks to the vascular pinpoint pattern and desquamative, peripheral collarette. Gener...

Introduction: Vitiligo is a specific, common, often heritable acquired disorder characterized by well-circumscribed milky white cutaneous macules and patches devoid of identifiable melanocyte. Treatment vitiligo, though quite frustrating, includes repigmentation therapies like Topical glucocorticoids, calcipotrieinene, PUVA (Psoralen + Ultraviolet Light A). The combination calcipotriol proves e...

Scalp psoriasis occurs in 50%-75% of patients with plaque psoriasis. It may be the only area of the body affected, or it may be associated with disease elsewhere, including psoriatic arthritis. Most cases are treated topically, usually with steroids and/or calcipotriol. In 2008, Health Canada and the US FDA approved a stable, once-daily 2-compound gel containing calcipotriol and betamethasone d...

We describe here the effects of three drugs that are either approved or have the potential for treating multiple sclerosis (MS) patients through the in vitro activities of human natural killer (NK) cells and dendritic cells (DCs). Our results indicate that 1,25(OH)2D3, the biologically active metabolite of vitamin D3, calcipotriol and FTY720 augment IL-2-activated NK cell lysis of K562 and RAJI...