OBJECTIVE To investigate the contributions of adenoid and tonsil size to childhood obstructive sleep apnea (OSA) and the interactions between adenotonsillar hypertrophy, age, and obesity in children with OSA. METHODS In total, 495 symptomatic patients were recruited. The patients were assigned to four groups according to age: toddler (age 1-3, n=42), preschool (age 3-6, n=164), school (age 6-...

AIM To examine the influence of protease inhibitors on tryptase release, and as a comparison the influence of the inhibitors on histamine secretion was assessed. METHODS Enzymatically dispersed cells from human tonsil were challenged with anti-IgE or calcium ionophore A23187 (CI) in the absence or presence of the tryptase and chymase inhibitors, and tryptase and histamine release was determin...

Tuberculosis of the tonsils is by no means a common condition, Mullin (1923), for example, in analysing 400 tonsillectomies found only 4.25 per cent cases of tuberculous tonsils. The present study is based on 2,477 tonsillectomies in the Madras General Hospital. This series covers a period of five years from January 1928 to December 1932. We, however, feel that this investigation is incomplete ...