This study demonstrates that ΔlogP(oct-tol) (difference between logP(octanol) and logP(toluene)) describes compounds propensity to form intramolecular hydrogen bonds (IMHB) and may be considered a privileged molecular descriptor for use in drug discovery and for prediction of IMHB in drug candidates. We identified experimental protocols for acquiring reliable ΔlogP(oct-tol) values on a set of c...

We present new VLA C-configuration H i imaging of the Lyα-emitting starburst galaxies Tol 1924−416 and IRAS08339+6517. The effective resolution probes neutral gas structures larger than 4.7 kpc in Tol 1924−416, and larger than 8.1 kpc in IRAS08339+6517. Both systems are revealed to be tidally interacting: Tol 1924−416 with ESO338−IG04B (6.6 = 72 kpc minimum separation), and IRAS08339+6517 with ...

The relationship between executive function and comorbid diagnoses in ADHD children is examined. One hundred six children between 7 and 15 years of age are assessed using the Tower of London (TOL), a test of executive function, and the Kiddie Schedule of Affective Disorders and Schizophrenia, Present and Lifetime Version, a diagnostic interview. All children met the diagnostic criteria for ADHD...

Locking is a popular deflation technique followed by many eigensolvers, where a converged eigenvector is frozen and removed from the iteration search space. Other deflation techniques that do not modify the matrix have less favorable numerical properties, so the alternative to locking is not to perform deflation at all. Without deflation, which we refer to as non-locking, converged eigenvectors...

The tree of life (ToL) is used variously as metaphor, model, and research tool to explore life’s evolution and genealogical relationships. It has broad appeal for multiple scientific communities and the public as a descriptive term covering life’s diversity. However, as biologists identify more entities and events to describe—including species, organisms, cells, genomes, gene families, extra-ch...

The upper operon of the TOL plasmid pWW0 of Pseudomonas putida encodes a set of enzymes involved in the conversion of toluene and xylenes to their carboxylic acid derivatives. The last gene of the upper operon, xylN, encodes a 465-amino-acid polypeptide which exhibits significant sequence similarity to FadL, an outer membrane protein involved in fatty acid transport in Escherichia coli. To anal...

drought stress is one of the most important dangers for increasing the yield and good production of crops in iran and the world. to evaluate the genetic diversity of rapeseed genotypes, identifying the drought resistance indices and drought tolerant genotypes, 16 genotypes were tested in a randomized complete block design (rcbd) with three replications and two different water regimes (irrigated...

Discourses can be stronger than facts and, therefore, harder to dismantle. For example, the extinction of Selk’nam is a fallacy that has remained for more century since it was decreed by scientific community itself, thus making their descendants invisible. Combining this invisibility with peatlands - original habitat project seeks dismantle these discourses reusing and resignifying same ninet...

this study was conducted to determine drought tolerance genotypes with superiority in different stressed environments. to screening quantitative indices of drought tolerance, genotypes of safflower (carthamus tinctorius l.) were tested in a complete randomized block design with three replications under two different water regimes (irrigated and rainfed). significant positive correlation was fou...

in order to comparison and determination of the best drought tolerance indices in sweet corn hybrids, an experiment was conducted using a randomized complete block design in split plot lay out with three replications at seed and plant improvement institute in karaj in 2006. three irrigation levels (irrigation after 75 as control, 100 and 125 millimeters cumulative evaporation from class a evapo...