BACKGROUND AND OBJECTIVES The aim of this study was to investigate inflammatory indicators and oxidative status in patients with asbestos exposure with and without mesothelioma and to compare results with data from healthy subjects. METHODS Eighty people with exposure to environmental asbestos and without any disease, 46 mesothelioma patients, and a control group of 50 people without exposure...

Using an approach involving physiologically based toxicokinetic (PBTK) modelling and Monte Carlo simulation (MCS), we investigated the impact of the biological variability affecting the parameters (e.g. physiological, physicochemical, biochemical) which determine toluene (TOL) kinetics on two exposure indicators (EIs): urinary excretion of o-cresol (o-CR), measured at the end of an 8 h exposure...

Cultural differences in time attitudes and their effect on timed neuropsychological test performance were examined in matched non-clinical samples of 100 Russian and American adult volunteers using 8 tests that were previously reported to be relatively free of cultural bias: Color Trails Test (CTT); Ruff Figural Fluency Test (RFFT); Symbol Digit Modalities Test (SDMT); and Tower of London-Drexe...

OBJECTIVE The study aimed to evaluate the pre-treatment and post-treatment oxidant capacity, antioxidant capacity and S100B protein levels in cases of diabetic ketoacidosis (DKA). METHODS The study included 49 pediatric patients diagnosed with DKA and a control group comprising 49 healthy children. Blood samples were obtained after confirmation of the DKA diagnosis and also after treatment. S...

The application of preexisting DNA hybridization techniques was investigated for potential in determining populations of specific gene sequences in environmental samples. Cross-hybridizations among two degradative plasmids, TOL and NAH, and two cloning vehicles, pLAFR1 and RSF1010, were determined. The detection limits for the TOL plasmid against a nonhomologous plasmid-bearing bacterial backgr...

BACKGROUND Both animals and plants respond rapidly to pathogens by inducing the expression of defense-related genes. Whether such an inducible system of innate immunity is present in the model nematode Caenorhabditis elegans is currently an open question. Among conserved signaling pathways important for innate immunity, the Toll pathway is the best characterized. In Drosophila, this pathway als...

Dalam praktiknya, sering terjadi sengketa lahan yang akan digunakan dalam pembangunan jalan tol, salah satunya ketidakmauan pemilik untuk membuatnya. Ketika pemerintah ingin membangun tol di atas tanah masyarakat, biasanya ada ganti rugi dibebankan kepada membayarnya tanah. Baik dibangun tersebut atau menolak menerima dari pemerintah. Sebaliknya , membeli harus mengikuti tahapan jelas dan pedom...

The title compound, C(56)H(56)Ge(4)O(2)·2CH(2)Cl(2) or Tol(8)Ge(4)O(2)·2CH(2)Cl(2) (Tol = p-CH(3)C(6)H(4)), was obtained serendipitously during the attempted synthesis of a branched oligogermane from Tol(3)GeNMe(2) and PhGeH(3). The mol-ecule contains an inversion center in the middle of the Ge(4)O(2) ring which is in a chair conformation. The Ge-Ge bond distance is 2.4418 (5) Å and the Ge-O bo...