We now realize, from the case of 2008 TC3’s discovery and subsequent impact in Sudan, that it is much more likely that a Near Earth Object (NEO) large enough to cause damage on the ground will be found (by the current Spaceguard Survey telescopes) on its "death plunge," providing a couple weeks of warning, than that a dangerous NEO will be found years or decades before impact. We also understan...

Recombinant adeno-associated virus 2 (AAV) virions were constructed containing a gene for resistance to neomycin (neoR), under the control of either the herpesvirus thymidine kinase (TK) gene promoter (vTK-Neo), or the human parvovirus B19 p6 promoter (vB19-Neo), as well as those containing an upstream erythroid cell-specific enhancer (HS-2) from the locus control region of the human beta-globi...

The goal was to examine the nature of social anhedonia using two validated measures and study their relationship to scores on the NEO-Five Factor Inventory (NEO-FFI). Nearly 1,900 college-aged participants completed the Chapman Revised Social Anhedonia Scale (RSAS), Anticipatory and Consummatory Interpersonal Pleasure Scale (ACIPS), and the NEO-FFI. Although both the RSAS and ACIPS were associa...

This article explores some concerns about the concept of neo-liberalism, suggesting that it has been stretched too far to be productive as a critical analytical tool. Neo-liberalism suffers from promiscuity (hanging out with various theoretical perspectives), omnipresence (treated as a universal or global phenomenon), and omnipotence (identified as the cause of a wide variety of social, politic...

BACKGROUND Gene-poor, degenerate Y chromosomes have evolved repeatedly from ordinary autosomes, but little is known about the processes that silence most genes on an evolving Y. RESULTS Here, I quantify relative expression levels of 58 gene pairs on the recently formed neo-sex chromosomes of Drosophila miranda, in order to test competing models of gene inactivation on its newly evolving Y chr...

This paper discusses Michael Dummett’s criticism of the Neo-Fregean conception of the context principle. I will present four arguments by Dummett that purport to show that the context principle is incompatible with platonism. I discuss and ultimately reject each argument. I will close this paper by identifying what I take to be a deeprooted tension in the Neo-Fregean project which might have mo...

William Davies’ The Limits of Neo-Liberalism: Authority, Sovereignty and the Logic of Competition (Sage, 2014) provides a searching new investigation of the meaning and implications of the neo-liberal project. Davies identifies neo-liberalism as centrally concerned with the replacement of politics by economics. He examines the consequent efforts of economic experts to make government amenable t...

Peer-to-peer, multiplayer games require secure event ordering, bounded latency between any two players, and a real-time transport protocol that includes congestion control. In the past, research has focused on solving one of these three issues, but has yet to address all of them in conjunction. In this paper, we design the NEO protocol to provide all three of these features in a fully-distribut...