The Chronopharmacokinetics of a single oral dose of theophylline was studied in rabbits. It was observed that morning (06.00 hr) dosing was characterized by significantly low rate of absorption (t 1/2a and Tmax) but higher extent of absorption (AUC0-alpha) compared to that after nocturnal dosing (22.00 hr). The plasma half life (t1/2el) was significantly less at night compared to that in daytim...

Maine, USA is the largest producer of wild blueberries (Vaccinium angustifolium Aiton), an important native North American fruit crop. Blueberry fields are mainly distributed in coastal glacial outwash plains which might not experience same climate change patterns as whole region. It to analyze blueberry and determine how they affect crop health so can be managed more efficiently under change. ...

The growth pattern of probiotics can be modified by changing their nutritional factors and physiological stage. Meanwhile, high intensity ultrasound (HIUS) employed to increase probiotics’ biomass. one-factor-at-a-time (OFAT) approach was investigate the influence medium (MRS broth, whole milk, skim milk), culture age (1 day 7 days old) parameters (time amplitude) on kinetic L. acidophilus. old...

Diurnal Temperature Range (DTR) is one of global warming indicator which using only daily minimum temperature (TMin) and maximum (TMax) for calculation. The study aims 1) to analyse trend TMax, TMin DTR over the early period 21st century (1987 - 2020) 2) forecast mid late (2021 2040 2041-2100) MIROC5 (rcp85) model, cooperated with EQM Statistical downscaling method. TMin, trends all periods wer...

Future climate projections provide vital information for preventing and reducing disaster risks induced by the global warming. However, little attention has been paid to change oriented towards carbon neutrality. In this study, we address projected changes in daily maximum (Tmax) minimum (Tmin) temperatures as well diurnal temperature range (DTR) over East Asia neutrality period of 2050–2060 un...

BACKGROUND Parametric-colored digital subtraction angiography using Tmax is almost a routine angiographic imaging procedure, currently. The current feasibility study is aimed to using the imaging to monitor treatment effects while embolizing indirect carotid-cavernous fistulas (CCF). METHODS Ten patients with CCFs receiving embolization and 40 patients with normal circulation time were recrui...

Background: Iodine-131 (I-131) is an effective treatment for differentiated thyroid carcinomas (DTC) after surgery. Salivary and lacrimal gland dysfunction has been described in patients receiving high doses of 1-131 due to radiation damage to salivary and lacrimal glands. Objective: This prospective study was conducted to determine the short term effect of oral 1-131 therapy administered to th...

BACKGROUND Lengthy microvascular procedures carry hypothermia risk, yet limited published data evaluate the overall impact of core temperature on patient and flap morbidity. Although hypothermia may contribute to complications, warming measures are challenged by conflicting reports of intraoperative hypothermia improving anastomotic patency. METHODS A retrospective review included all free fl...